by South Australian Health and Medical Research Institute (SAHMRI) Credit: Shutterstock A team of researchers from SAHMRI and Flinders University has found a link between the type of microbiome that repopulates the gut following antibiotics and shortened lifespan in mice. The study recently published in Cell Reports, is the first of its kind to examine the long-term effects of exposing...
Tag: <span>Microbiome</span>
New report explains microbiome impact on glucose control
THE GINGER NETWORK IMAGE: Pendulum Glucose Control, the first-of-its-kind formulation of both probiotics and a prebiotic, is changing dietary management of type 2 diabetes. In a double-blind, randomized placebo-controlled study, Pendulum Glucose Control reduced A1c levels by 0.6% compared to placebo and generated a 33% reduction in postprandial glucose spikes (Area Under the Curve or...
Study may explain the microbiome-immunotherapy connection
by Weizmann Institute of Science Digitally colored electron microscopy images of melanoma cells harboring bacteria. Credit: Weizmann Institute of Science Cancer immunotherapy may get a boost from an unexpected direction: bacteria residing within tumor cells. In a new study published in Nature, researchers at the Weizmann Institute of Science and their collaborators have discovered that the...
The skin microbiome
Michael Eisenstein Credit: Andrew Khosravani In contrast to the gut, which offers a near-ideal habitat for the growth of fermentative bacteria, the skin is an inhospitable expanse. Much of the epidermal layer that protects humans from the elements is dry, salty, acidic and nutrient-poor. The exceptions are the oases around lipid-rich hair follicles. Despite this...
Turning microbiome research into a force for health
The microbiome comprises trillions of microorganisms living on and inside each of us. Historically, some researchers have guessed at its role in human health, but in the last decade or so genetic sequencing techniques have illuminated this galaxy of microorganisms enough to study it in detail. As researchers unravel the complex interplay between our bodies and microbiomes, they are...
The Impact of the Microbiome on Immunity to Vaccination in Humans
Vaccines are the most effective means available for preventing infectious diseases. However, vaccine-induced immune responses are highly variable between individuals and between populations in different regions of the world. Understanding the basis of this variation is, thus, of fundamental importance to human health. Although the factors that are associated with intra- and inter-population variation in...
New Microbiome Health Index provides a “credit score for your gut”
By Rich Haridy, September 15, 2020 The proposed test will not detect specific disease but instead offer an indication of one’s general health status Researchers at the Mayo Clinic have developed a test that can predict a person’s general health status by measuring the levels of 50 gut microbial species. Called the Gut Microbiome Health...
A single-cell atlas of nerve cells in the gut reveals web of connections
by Karen Zusi, Broad Institute of MIT and Harvard Cross-section of mouse tissue expressing GFP (green) in all ENS nuclei, and tdTomato (red) in all ENS cells (neurons and glia). The section is also stained with DAPI (blue) to mark all nuclei and an anti-TUBB3 antibody (white) to mark all neurons. Credit: Eugene Drokhlyansky, Chris...
Penis microbiota predicts if a man’s female partner will develop bacterial vaginosis
Bacterial vaginosis is triggered by BV-related bacteria present in some men’s penile microbiome FRONTIERS Bacterial Vaginosis (BV) is an infection affecting more than 20% of women worldwide. Caused by a change in the natural balance of the vaginal microbiota, this infection can lead to adverse outcomes in pregnancy as well as more susceptibility to sexually...
Gut microbiome translates stress into sickle cell crises
ALBERT EINSTEIN COLLEGE OF MEDICINE July 30, 2020–(BRONX, NY)–A new study shows how chronic psychological stress leads to painful vessel-clogging episodes–the most common complication of sickle-cell disease (SCD) and a frequent cause of hospitalizations. The findings, made in mice, show that the gut microbiome plays a key role in triggering those episodes and reveals possible...