by Julius-Maximilians-Universität Würzburg The pictures show the same stomach organoids: It shows the cell nuclei (blue) and the skeleton of the cell (pink) as a cross-section of the organoids. In grey is the microscopic picture of the organoids. A single organoid here is about a quarter millimeter in size. Credit: Julius-Maximilians-Universität Würzburg, JMU Why is...
Washington, DC – June 20, 2020 – Two types of tests are used to track SARS-CoV-2. Reverse transcriptase PCR (rt-PCR) tests for current infection. Antibody tests reveal that an infection has taken place, even long after the fact. Each of 2 papers published in the Journal of Clinical Microbiology (JCM) addresses one of these testing...
by Margareta Gustafsson Kubista, University of Gothenburg There is a clear link between improved gut microbiota and one of our most common cholesterol-lowering drug groups: statins. This is evident from a European study involving researchers from the University of Gothenburg. Scientists have previously found an association between the gut microbiota and various metabolism-related and cardiovascular...
by University of North Carolina Health Care Hepatitus A virus particles (pink) trapped in lysosomes (yellow intracellular organelles), unable to initiate replication in the cytoplasm of cells due to UCGC enzyme being knocked out. Credit: Maryna Kapustina, PhD, UNC School of Medicine How hepatitis A virus (HAV) manages to enter liver cells called hepatocytes and...
by Emily Ayshford, University of Chicago More than 1.7 million Americans develop sepsis each year, and more than 270,000 die from it. The condition—which happens when the body has an extreme response to a bacterial or viral infection, causing a chain reaction that can lead to organ failure and death—has few strategies for treatment. That’s...
By Dr. Maho Yokoyama, Ph.D.Reviewed by Michael Greenwood, M.Sc. Why a Gluten Free Diet? Gluten is a protein found in grains such as wheat, barley, and rye, and is comprised of gliadins. For some people, eating foods that contain gluten can cause digestive problems due to gluten-related disorders. Gluten-related disorders can range from mild to severe in symptoms, and include celiac disease...
Signaling through interleukin-10 (IL-10) receptors on gut immune cells plays a critical role in protecting the gut lining and microbiota from disruption caused by whipworms, according to a study published January 31 in the open-access journal PLOS Pathogens by María Duque-Correa of the Wellcome Sanger Institute in the UK, and colleagues. The human gut is...
PHILADELPHIA — The probiotic VSL#3 and fecal microbiota transplantation could help induce remission in patients with ulcerative colitis, according to a systematic review and meta-analysis of randomized controlled trials. There is “abundant evidence” that the intestinal microbiome plays an integral role in the pathogenesis of ulcerative colitis, said Mina Fransawy Alkomos, MD, from New York...
Despite Graves’ disease and Graves’ orbitopathy affecting around 3 million Europeans and costing billions of euros, treatments can only control symptoms. INDIGO identified risk factors, studied microbiota composition and tested probiotics to improve health outcomes. Credit: Perception7, Shutterstock Graves’ disease (GD)—the commonest cause of an overactive thyroid gland—is a chronic autoimmune condition characterized by the...
A broad range of metabolic and inflammatory diseases is associated with alterations in gut microbiota composition and metabolic potential. Until now, sequencing-based gut microbiota research has described such dysbiotic states in terms of proportional shifts in microbiome composition. However, when it comes to the gut bacterial content and how it relates to health, it’s not...
