Tag: <span>microbiota</span>

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Count your blessings: Quantitative microbiome profiling

A broad range of metabolic and inflammatory diseases is associated with alterations in gut microbiota composition and metabolic potential. Until now, sequencing-based gut microbiota research has described such dysbiotic states in terms of proportional shifts in microbiome composition. However, when it comes to the gut bacterial content and how it relates to health, it’s not...

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Type 1 diabetes and the microbiota—MAIT cells as biomarkers and new therapeutic targets

Together with colleagues from AP-HP Necker–Enfants Malades Hospital in Paris, scientists from the Cochin Institute (CNRS / INSERM / Paris Descartes University) have discovered that the onset of type 1 diabetes is preceded by modification of MAIT lymphocytes. These cells—associated with mucosae and able to recognize elements of the microbiota—could therefore serve as new biomarkers...