UNIVERSITY OF CALIFORNIA – IRVINE IMAGE: “EARLY LIFE ADVERSITY IS A ROBUST RISK FACTOR FOR LIFE-LONG ABERRANT RESPONSES TO STRESS, WHICH CAN CONTRIBUTE TO SEVERAL MAJOR MENTAL ILLNESSES, INCLUDING DEPRESSION, IN ADULTHOOD. OUR FINDINGS IDENTIFY AN IMPORTANT ROLE FOR ELA-INDUCED ALTERATIONS OF MICROGLIAL ACTIONS DURING A SENSITIVE BRAIN DEVELOPMENT PERIOD, RESULTING IN AUGMENTED EXCITATORY SYNAPSES...
