by Massachusetts Institute of Technology MIT researchers have developed microparticles that can be tuned to deliver their payload at different time points, which could be used to create “self-boosting” vaccines. Credit: Second Bay Studios, edited by MIT News Most vaccines, from measles to COVID-19, require a series of multiple shots before the recipient is considered...
MIT engineers are using computing modeling to prevent microparticles from clogging during injections. Microparticles offer a promising way to deliver multiple doses of a drug or vaccine at once because they can be designed to release their payload at specific intervals. However, the particles, which are about the size of a grain of sand, can...
UNIVERSITY OF WISCONSIN-MADISON MADISON, Wis. — University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans. The technology relies on inserting into...
A NOVEL FORMULATION OF THE PROSTATE CANCER DRUG ABIRATERONE ACETATE – CURRENTLY MARKETED AS ZYTIGA – WILL DRAMATICALLY IMPROVE THE QUALITY OF LIFE FOR PEOPLE SUFFERING FROM PROSTATE CANCER.view more CREDIT: HAYLEY SCHULTZ/UNISA A novel formulation of the prostate cancer drug abiraterone acetate – currently marketed as Zytiga – will dramatically improve the quality of...
White blood cells called neutrophils may be central to the immune system overreaction that can kill COVID-19 patients. New research finds that rod-shaped particles can take them out of circulation. The top cause of death for COVID-19 patients echoes the way the 1918 influenza pandemic killed: their lungs fill with fluid and they essentially drown....
Pharmaceuticals owe their effects mostly to their chemical composition, but the packaging of these drugs into specific physical formulations also need to be done to exact specifications. For example, many drugs are encapsulated in solid microparticles, the size and shape of which determine the timing of the drug’s release and its delivery to specific parts...
At the University of Alabama at Birmingham, scientists have developed a new microparticle that carries doxorubicin chemo load, that can be imaged within the body and then made to release the cargo using external ultrasound. The polymer particles consist of layers of tannic acid and poly(N-vinylpyrrolidone), or TA/PVPON, both fairly biocompatible substances. They are generated over a...
