BARCELONA — For the first time, new research shows that taking a specific class of migraine medication during the prodromal phase reduces the development and severity of the subsequent headache. In the randomized, placebo-controlled crossover PRODROME trial, treatment with ubrogepant (Ubrelvy) 100 mg, one of the new CGRP receptor antagonists, during the prodrome prevented the...
Tag: <span>Migraine</span>
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A large international study of migraine reveals new biological pathways for treatment
by deCODE genetics Credit: Pixabay/CC0 Public DomainA large international study led by deCODE Genetics on the genetics of migraine provides novel insights into the biology of migraine enabling detection of rare variants protecting against migraine, opening an avenue for potential development of novel drug targets. In a study published in Nature Genetics a group of...
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New study shows common blood pressure meds underused for migraine
by George Institute for Global Health Credit: Pixabay/CC0 Public Domain The first known large-scale review of international studies on the positive effect of blood pressure (BP) medicines across all classes in preventing migraine shows these common drugs could be used much more widely, at low cost, than is the case with current practice, according to a new...
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Head-to-Head Comparison of 25 Migraine Meds Reveals Top Options
Megan Brooks May 02, 2023 When it comes to relieving migraine headache, triptans, ergots, and antiemetics are the most effective classes of medications, a new real-world analysis of data on more than 3 million migraine attacks shows. Dr Chia-Chun Chiang The findings “align with results of clinical trials and recommendations from clinical treatment guidelines” and provide insights to complement clinical practice, study investigator Chia-Chun...
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Migraine as a neurological condition
By Yale University Anyone who thinks of a migraine as “just a headache” has likely never had one, as the condition can be debilitating and painful. Migraine is a neurologic disorder that not only causes headaches, but often also a constellation of symptoms that can impact daily living, explains Jason Sico, MD, MHS, a Yale...
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Genetic links between migraine and blood sugar levels confirmed
by Queensland University of Technology The forest plot demonstrates the odds ratios (ORs) and 95% confidence intervals (CIs) for MR analyses examining the causal effects of glycemic traits on migraine (A) and headache (B). IVW Inverse variance weighted was employed as the primary analysis, GSMR Generalized summary data-based Mendelian Randomisation was used as a sensitivity...
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Migraine associated with increased risk for pregnancy complications
by Brigham and Women’s Hospital Credit: Unsplash/CC0 Public Domain Women are disproportionately affected by migraine, especially during their reproductive years. However, the relationship between migraine and adverse pregnancy outcomes has not been well understood. A new study by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, analyzed...
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Multiple chemical sensitivity identified in some migraine patients
One in five migraine patients has multiple chemical sensitivity (MCS), according to a study recently published in the Journal of Occupational Health. Keisuke Suzuki, M.D., Ph.D., from Dokkyo Medical University in Mibu, Japan, and colleagues examined the relationship between MCS and migraine using data from 95 consecutive patients in an outpatient headache clinic. Headache-related disability was...
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Abortion Ban May Mean Denial of Effective Drugs for Women with MS, Migraine, Epilepsy
The dissolution of Roe v. Wade is expected to lead to abortion bans or severe restrictions in as many as 28 states. These new restrictions may have life-changing and even life-threatening consequences in these states for women of childbearing age with conditions like migraine, multiple sclerosis (MS) and epilepsy. In their perspective article, published in JAMA Neurology,...
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Review: Transcranial direct current stimulation eases migraine
Credit: Pixabay/CC0 Public Domain Transcranial direct current stimulation (tDCS) is effective and safe for migraine, according to a review published online April 19 in CNS Neuroscience and Therapeutics. Peiwei Hong, from Sichuan University in Chengdu, China, and colleagues conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to examine the efficacy and safety of tDCS for migraine. The...