Defective mitochondria – the ‘batteries’ that power the cells of our bodies – could in future be repaired using gene-editing techniques. Scientists at the University of Cambridge have shown that it is possible to modify the mitochondrial genome in live mice, paving the way for new treatments for incurable mitochondrial disorders. Our cells contain mitochondria,...
Tag: <span>mitochondrial disorder</span>
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Japanese-European research team discovers novel genetic mitochondrial disorder
by Fujita Health University A Japanese-European team of scientists described novel mutations in the LIG3 gene, which plays a key role in mitochondrial DNA replication. Normally, mitochondrial DNA is repaired and replicated by LIG3 activity, but if the gene contains mutations, enzymes necessary for energy production are not produced, potentially leading to central nervous system...