INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) IMAGE: MITOCHONDRIA (IN BLUE), ENDOSOMES (IN WHITE) AND MITOCHONDRIAL DNA (IN ORANGE) FROM A HEALTHY MUSCLE CELL CREDIT: IRB BARCELONA Fragmentation and elongation of mitochondria lead to the activation of inflammatory processes in muscle cells, which result in the development of muscle atrophy, and a diminished resistance to...
Tag: <span>mitochondrial dynamics</span>
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Age-related decline in two sirtuin enzymes alters mitochondrial dynamics, weakens cardiac contractions
by Anne Delotto Baier, University of South Florida Credit: Unsplash/CC0 Public Domain Sirtuins are a family of anti-aging proteins that help regulate cellular lifespan, metabolism, and resistance to stress. The potential protective effect of these sirtuin enzymes in age-related diseases, including cardiovascular diseases, remains an area of intense investigation. Now, a new preclinical study led by...