UNIVERSITY OF FREIBURG IMAGE: MODEL OF THE BETA-BARREL PROTEIN PORIN FROM BAKER’S YEAST FOUND IN THE MITOCHONDRIAL OUTER MEMBRANE. CREDIT: ILLUSTRATION: CHRISTOPHE WIRTH/UNIVERSITY OF FREIBURG Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is...
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH IMAGE: MTCH2 ACTS AS A DOORWAY FOR PROTEINS INTO THE OUTER MITOCHONDRIAL MEMBRANE. CREDIT: MARIA GUNA Mitochondria — the organelles responsible for energy production in human cells — were once free-living organisms that found their way into early eukaryotic cells over a billion years ago. Since then, they have merged seamlessly...
UNIVERSITY OF FREIBURG IMAGE: MODEL OF BETA-BARREL MEMBRANE PROTEIN PORE BIOGENESIS AT THE SORTING AND ASSEMBLY MACHINERY (SAM) OF THE OUTER MITOCHONDRIAL MEMBRANE. CREDIT: ILLUSTRATION: NILS WIEDEMANN Mitochondria are vital for the human body as cellular powerhouses: They possess more than 1,000 different proteins, required for many central metabolic pathways. Disfunction of these lead to...
