Tag: <span>Modifier gene</span>

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Modifier gene may explain why some with cystic fibrosis are less prone to infection

UNIVERSITY OF CALIFORNIA – SAN DIEGO Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Due to this mutation, the CFTR protein doesn’t embed in cell membranes to form a channel for chlorine ions the way it should. As a result, mucus-producing cells secrete a thicker-than-normal mucus...