Tag: <span>molecular changes</span>

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Study links molecular changes to long COVID a year after hospitalization
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Study links molecular changes to long COVID a year after hospitalization

by The Mount Sinai Hospital Study workflow. Schematics of the study design, analysis workflow and validation. a, Summary of the cohort studied and data collected. b, Strategy for CTS differential expression testing for PASC symptoms. c, Strategy for distinguishing DEGs by whether or not their differential expression is dependent on anti-spike antibody titers. d, Validation strategies employed using independent...

New research identifies injury-induced molecular changes in chondrocytes, at single-cell level
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New research identifies injury-induced molecular changes in chondrocytes, at single-cell level

by Anne M Stark,  Lawrence Livermore National Laboratory Gene expression in mouse knee joint chondrocytes was analyzed using single-cell RNA sequencing, which identified nine chondrocyte subpopulations with distinct molecular profiles. Credit: Lawrence Livermore National Laboratory Articular cartilage is a connective tissue lining the surfaces of joints. When the cartilage severely wears down, it leads to osteoarthritis...