by Medical University of Vienna Credit: Kateryna Kon/Shutterstock Heart attacks and strokes arising from atherosclerosis, which is driven by the accumulation of lipids in the inner linings of arteries, are responsible for about one third of deaths worldwide. Accordingly, atherosclerosis is the focus of intense research aimed at the development of novel effective treatments. A team of researchers from MedUni...
by Hokkaido University When mice that exhibit SLE-like symptoms are subjected to sleep deprivation stress, their neurons exhibit abnormal growth (left). When IL12 and 23 are blocked, the abnormal growth is reversed (right). Credit: Nobuya Abe et al, Annals of the Rheumatic Diseases (2022) Systemic lupus erythematosus (SLE) is an autoimmune disease that affects all the organ...
by National Institutes of Health Credit: Pixabay/CC0 Public Domain Researchers from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of...
