by The Scripps Research Institute Researchers discovered that when the protein DNMT3B becomes S-nitrosylated in the presence of nitric oxide (NO), cancer-related genes become activated, leading to the proliferation of tumor cells. Credit: Scripps Research Scientists at Scripps Research, with collaborators in Japan, have discovered how a “poisoned” form of a protein could set off a cascade of...
by Heidelberg University Cultured neurons from the striatum of mice. Credit: Thomas Lissek / Hilmar Bading A molecular switch influences addiction behavior and determines how strong the response to addictive drugs is. A research team at Heidelberg University and the Sorbonne University in Paris (France) made the discovery in mice treated with cocaine. The researchers...
by Sarah C. P. Williams, Gladstone Institutes Scientists at Gladstone Institutes discovered a gene that could prevent fibrosis in the heart. Shown here, Michael Alexanian, a postdoc in the Srivastava Lab and first author of the new study. Credit: Michael Short/Gladstone Institutes A healthy heart is a pliable, ever-moving organ. But under stress—from injury, cardiovascular disease,...
by University of California – Berkeley Chronic inflammation, which results when old age, stress or environmental toxins keep the body’s immune system in overdrive, can contribute to a variety of devastating diseases, from Alzheimer’s and Parkinson’s to diabetes and cancer. Now, scientists at the University of California, Berkeley, have identified a molecular “switch” that controls...
