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Antiviral used to treat cat coronavirus also works against SARS-CoV-2
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Antiviral used to treat cat coronavirus also works against SARS-CoV-2

by Gillian Rutherford, University of Alberta Faculty of Medicine & Dentistry Biochemist Joanne Lemieux worked with three other University of Alberta researchers on a new study showing that a drug that cures deadly peritonitis in cats also works well enough against the coronavirus that causes COVID-19 to fast-track it into human clinical trials. Credit: University...

Synthetic coating for the GI tract could deliver drugs or aid in digestion
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Synthetic coating for the GI tract could deliver drugs or aid in digestion

MIT engineers devise a temporary film that may help treat diabetes, infections, and other conditions MASSACHUSETTS INSTITUTE OF TECHNOLOGY POSTDOCTORAL ASSOCIATE JUNWEI LI, LEAD AUTHOR OF THE STUDY, HOLDS AN EXAMPLE OF A CAPSULE CONTAINING THEIR ENZYME. CREDIT: IMAGE BY MELANIE GONICK/MIT By making use of enzymes found in the digestive tract, MIT engineers have...

Researchers find method to regrow cartilage in the joints
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Researchers find method to regrow cartilage in the joints

by Christopher Vaughan, Stanford University Medical Center Researchers at the Stanford University School of Medicine have discovered a way to regenerate, in mice and human tissue, the cushion of cartilage found in joints. Researchers at the Stanford University School of Medicine have discovered a way to regenerate, in mice and human tissue, the cushion of...

New ‘molecular computers’ find the right cells
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New ‘molecular computers’ find the right cells

by University of Washington An artist’s depiction of a Co-LOCKR nano-device coming together on the surface of a cell that has the right combination of cell surface markers. Credit: UW Medicine Institute for Protein Design Scientists have demonstrated a new way to precisely target cells by distinguishing them from neighboring cells that look quite similar....

The behaviour of therapeutic antibodies in immunotherapy
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The behaviour of therapeutic antibodies in immunotherapy

Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells. However, in the more than 20 years since their use began, the molecular mechanisms that underlie this therapy are still little understood. For the first time, scientists from the...

Scientists replace malfunctioning ‘vacuum cleaner’ cells linked to neurological disorders
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Scientists replace malfunctioning ‘vacuum cleaner’ cells linked to neurological disorders

FUDAN UNIVERSITY SCIENTISTS FROM FUDAN UNIVERSITY DEVELOPED NOVEL STRATEGIES ACHIEVING ALLOGENEIC MICROGLIA REPLACEMENT IN THE CENTRAL NERVOUS SYSTEM. view more CREDIT: IMAGE CREDIT: XU ET AL, 2020, CELL REPORTS Researchers at Fudan University in Shanghai, China have developed three different techniques that successfully replace almost all malfunctioning microglia – each technique with its own advantage...

Study reveals immune-system paralysis in severe COVID-19 cases
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Study reveals immune-system paralysis in severe COVID-19 cases

by Stanford University Medical Center 3D print of a spike protein of SARS-CoV-2, the virus that causes COVID-19–in front of a 3D print of a SARS-CoV-2 virus particle. The spike protein (foreground) enables the virus to enter and infect human cells. On the virus model, the virus surface (blue) is covered with spike proteins (red)...

Cutting edge synthetic peptides block SARS-CoV-2 (COVID-19)
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Cutting edge synthetic peptides block SARS-CoV-2 (COVID-19)

By Sally Robertson, B.Sc. Researchers at Ligandal Inc., the University of California San Francisco and Toyota Technological Institute at Chicago, have designed novel synthetic peptides that potently inhibit the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to infect host cells. The team’s SARS-BLOCK™ peptides competitively inhibit the receptor-binding domain (RBD) on the SARS-CoV-2...

Osteopontin, a protein not always as bad as it is made out to be
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Osteopontin, a protein not always as bad as it is made out to be

The UPV/EHU-University of the Basque Country shows that maintaining osteopontin delays the onset of metabolic fatty liver disease during ageing UNIVERSITY OF THE BASQUE COUNTRY THE STUDY INDICATES THAT OSTEOPONTIN IS NECESSARY TO PREVENT THE EARLY ONSET OF NON-ALCOHOLIC FATTY LIVER DISEASE LINKED TO AGEING view more Metabolic fatty liver disease, known as non-alcoholic fatty...

A targeted treatment for emphysema? Small engineered peptide maintains lung tissue in animal models
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A targeted treatment for emphysema? Small engineered peptide maintains lung tissue in animal models

by Children’s Hospital Boston Children’s Hospital tested PR1P in lung cells and mouse models of emphysema, they found that it protected VEGF from being degraded, prevented cell death, and protected the lung. Credit: Hao Wu, PhD, Boston Children’s Hospital Emphysema is a progressive, debilitating lung disease in which the lung’s breathing sacs, or alveoli, enlarge,...