by Goethe University Frankfurt am Main Infection of primary human cells with mpox virus (MPXV) isolates obtained from patients during the current outbreak and sensitivity to antiviral drugs. Credit: New England Journal of Medicine (2022). DOI: 10.1056/NEJMc2212136 The mpox virus is closely related to the smallpox virus (variola virus), which caused large, deadly outbreaks before it was...
by Boston University School of Medicine Chemical structure of CMLDBU6128 (1) and overview of exploratory PDPM analog libraries based on variation at C3 (R1), C7 (R2), and N2 (R3). The red numbers represent sites of potential modifications described in this study. Credit: Antimicrobial Agents and Chemotherapy (2022). DOI: 10.1128/aac.00841-22 Monkeypox is a viral zoonosis (a virus transmitted to humans from...
by University of Oxford Plan of room A representing the sites of samples and Ct values. *Air samples were collected over a period of 10 min at a rate of 50 L/min (500 L total). Ct=quantitative PCR crossing threshold value of monkeypox DNA detected. Credit: The Lancet Microbe (2022). DOI: 10.1016/S2666-5247(22)00257-9 Monkeypox virus can be shed into...
by Hong Kong University of Science and Technology The figure shows that, for two example proteins that are targeted by VACV-vaccine-induced antibodies, the 2022 monkeypox virus (MPXV-2022) does not comprise any new mutations relative to the previously observed monkeypox virus (MPXV-CB). Credit: HKUST & UoM New research has suggested that recommended vaccinia virus (VACV)-based vaccines...
BARCELONA INSTITUTE FOR GLOBAL HEALTH (ISGLOBAL) Viral DNA can be frequently detected in different clinical samples from monkeypox-infected patients, including saliva and semen, according to a new study led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the “la Caixa” Foundation, and the Hospital Clínic of Barcelona. The study, published in Eurosurveillance,...
