Hallie Levine A treatment used to treat acute COVID-19 infection has also been found to be effective against long COVID, a new small study has found. The research, which assessed the benefits of monoclonal antibodies, suggests relief may finally be ahead for millions of Americans with long COVID for whom treatment has remained elusive. The...
Tag: <span>monoclonal antibody</span>
Post
Promising investigational therapeutic monoclonal antibody to treat chronic hepatitis B and D infections
by Deutsches Zentrum für Infektionsforschung Credit: Journal of Hepatology (2023). DOI: 10.1016/j.jhep.2023.07.003 Affecting hundreds of millions of people, chronic hepatitis B is a widespread global health problem for which there is as yet no cure. In a preclinical study involving the German Center for Infection Research (DZIF), Heidelberg University Hospital, University Medical Center Hamburg-Eppendorf and the US company Vir...
Post
Small study shows promise for antimalarial monoclonal antibody to prevent malaria
by University of Maryland School of Medicine Colorized electron micrograph showing malaria parasite (right, blue) attaching to a human red blood cell. The inset shows a detail of the attachment point at higher magnification. Credit: NIAID A monoclonal antibody treatment was found to be safe, well tolerated, and effective in protecting against malaria in a...
Post
Novel monoclonal antibody therapy for SARS-CoV-2
by Marla Paul, Northwestern University Graphical abstract. Credit: Journal of Clinical Investigation (2022). DOI: 10.1172/JCI162282 An entirely new approach to monoclonal antibody therapy shows that targeting the more genetically stable internal protein of the SARS-CoV-2 virus rather than the surface spike protein can also clear SARS-CoV-2, reports a study from Northwestern Medicine and the University of Illinois...
Post
Monoclonal antibody improves cat allergen immunotherapy
NIH/NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES IMAGE: A CAT CREDIT: NIAID An experimental approach to enhancing a standard cat allergy treatment made it more effective and faster acting, and the benefits persisted for a year after treatment ended, a study supported by the National Institutes of Health has found. The findings were published Monday...
Post
Monoclonal antibody prevents malaria in U.S. adults
One injection of a candidate monoclonal antibody (mAb) known as L9LS was found to be safe and highly protective in U.S. adults exposed to the malaria parasite, according to results from a National Institutes of Health Phase 1 clinical trial published in The New England Journal of Medicine. Additional clinical trials evaluating if L9LS can prevent malaria over six to 12...
Post
A myeloma-targeting monoclonal antibody offers new hope for treating multiple myeloma
by Osaka University Summary of the research. Credit: Naoki Hosen Multiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Japan have recently found that a common component of amino acid transporters, CD98 heavy chain, represents an effective monoclonal antibody target in treating MM. In a...
Post
New monoclonal antibody shows promise for severe asthma
by National Jewish Health Credit: DOI: 10.1056/NEJMoa2024257 A new monoclonal antibody therapy shows promise in offering an alternative treatment for patients suffering from moderate-to-severe asthma. Research led by Michael E. Wechsler, MD, MMSc, director of the National Jewish Health Cohen Family Asthma Institute, found that itepekimab was safe and effective in a phase 2 trial...
Post
COVID-19: Monoclonal antibody combo helps high-risk people avoid hospital
Share on Pinterest New research suggests that a combination of two monoclonal antibodies can be an effective COVID-19 treatment. William Taufic/Getty Images A new study finds that a combination of two monoclonal antibodies can help high-risk COVID-19 patients avoid being hospitalized. In a study involving nearly 1,400 people with mild to moderate cases of COVID-19,...
Post
Monoclonal antibody prevents HIV infection in monkeys, study finds
by Franny White, Oregon Health & Science University HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia An experimental, lab-made antibody can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows. The results will inform a future human clinical trial evaluating leronlimab as potential pre-exposure prophylaxis, or PrEP,...
- 1
- 2