by Boston University School of Medicine Flow Diagram for Inclusion and Exclusion of Patients. Credit: JAMA Network Open (2023). DOI: 10.1001/jamanetworkopen.2023.8655 A thyroid storm is characterized by high-circulating thyroid hormones (severe hyperthyroidism) that leads to life-threatening acute end-organ damage, including neurologic dysfunction, cardiogenic shock, hepatic failure, cardiac arrhythmias, and high mortality. Current treatment guidelines recommend using the thyroid drug propylthiouracil...