by Justin Jackson , Medical Xpress Credit: CC0 Public Domain A research collaboration led by the University of Chinese Academy of Sciences, China, investigated the role of CHIT1, a protein associated with microglia, in aging. In a paper, “CHIT1-positive microglia drive motor neuron aging in the primate spinal cord,” published in Nature, the group identifies...
MASSACHUSETTS GENERAL HOSPITAL BOSTON – The antiepileptic drug ezogabine reduced pathologic excitability of cortical and spinal motor neuron cells that are early signs of clinical dysfunction in people with amyotrophic lateral sclerosis (ALS), according to a study conducted by the Neurological Clinical Research Institute of Massachusetts General Hospital (MGH). In addition to providing a clearer understanding of...
