Written by Stacia Woodcock, PharmD | Reviewed by Joshua Murdock, PharmD, BCBBS Updated on November 10, 2022 Key takeaways: Acetaminophen (Tylenol) and ibuprofen (Advil, Motrin) are both over-the-counter (OTC) medications for pain. Acetaminophen and ibuprofen work differently in the body. They are also cleared from the body by different organs. This makes it safe to...
