Tag: <span>mRNA delivery</span>

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Researchers discover new lipid nanoparticle that shows muscle-specific mRNA delivery, reduces off-target effects.
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Researchers discover new lipid nanoparticle that shows muscle-specific mRNA delivery, reduces off-target effects.

by Kate Richards, University of Toronto—Leslie Dan Faculty of Pharmacy A team of researchers based at the University of Toronto’s (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle, iso-A11B5C1, that enables muscle-focused mRNA delivery while minimizing off-target delivery to other tissues. Credit: Steve Southon, University of Toronto A...

Scientists develop novel mRNA delivery method using extracellular vesicles
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Scientists develop novel mRNA delivery method using extracellular vesicles

by University of Texas M. D. Anderson Cancer Center CNP generates large quantities of EVs loaded with COL1A1 mRNA. a, Schematic representation of CNP-generated EVs for targeted nucleic acid delivery. b, EV number per cell produced by untreated nHDFs in PBS buffer as control, BEP or CNP with PBS buffer only in 24 h (n = 3 for each group; *P = 0.048...