Moderna and Merck have presented promising results from their phase 2b clinical trial that investigated a combination of a messenger RNA (mRNA) vaccine and a cancer drug for the treatment of melanoma. Is mRNA set to shake up the world of cancer treatment? This is certainly what Moderna seems to think; the pharmaceutical company has...
Tag: <span>mRNA vaccine</span>
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mRNA Vaccine Cuts COVID-Related Guillain-Barré Risk
Kelli Whitlock Burton TOPLINE:The risk for Guillain-Barré syndrome (GBS) is six times higher in people with COVID-19 in the 6 weeks following infection, according to a new study that also showed receipt of the Pfizer-BioNTech mRNA vaccine reduced GSB risk by 59%. METHODOLOGY:The nested-case control study analyzed data from the largest healthcare provider in Israel...
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Is the Novavax COVID Vaccine Better than mRNA Vaccines? What We Know So Far
Novavax’s protein-based vaccine is the latest FDA-authorized COVID booster available this fall. Here’s what you should know By Sara Reardon on October 16, 2023 As the updated COVID vaccines roll out around the country, one more competitor has joined the mix. In early October the U.S. Food and Drug Administration authorized a new booster shot made by the...
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Moderna is safest, most effective mRNA vaccine against COVID-19 for older adults, study shows
by Brown University Credit: CC0 Public Domain While mRNA vaccines against COVID-19 have been found to be safe and effective for the general population, in-depth evidence about safety and effectiveness for older adults and individuals with chronic health conditions is more limited. To address that gap, a team led by Brown University researchers conducted the largest...
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Pure capped mRNA vaccine opens the door to more effective vaccines with lower chances of inflammation
by Nagoya University Pure capped mRNA vaccine opens the door to more effective vaccines with lower chances of inflammation. Credit: Mizuki Tada A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA. This “Purecap” technique extracted up to 100%...
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Which mRNA Vaccine Poses a Lower Risk for Myocarditis?
F. Perry Wilson, MD, MSCE November 08, 2022 Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I’m Dr F. Perry Wilson of the Yale School of Medicine. Let me start with a noncontroversial statement: A small number of individuals who receive an mRNA vaccine will develop myocarditis. Myocarditis is a side effect of...
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An mRNA vaccine with a twist—it copies itself—protects against COVID-19
21 APR 2022 6:35 PM BY JON COHEN The Arcturus Therapeutics COVID-19 vaccine contains a strand of messenger RNA (multicolored) that self amplifies after injection and then is translated by cells into the viral spike protein (purple). A third messenger RNA (mRNA) vaccine appears to have proved its worth against COVID-19. And although it is...
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Study shows mRNA vaccine technology can be used for HIV vaccines
by Sarah Avery, Duke University Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.110514 Using mRNA technology like that in the COVID-19 vaccines, researchers have demonstrated a successful way to deliver a potential HIV vaccine, researchers at Duke Human Vaccine Institute report. Publishing online March 15 in the journal Cell Reports, the research team describes an important advancement...
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mRNA vaccine makers set sights on shingles and the Epstein-Barr virus
By Rich Haridy January 05, 2022 As Moderna works on a mRNA vaccine against the Epstein-Barr virus, Pfizer sets its mRNA sights on a shingles vaccineMattLphotography/Depositphotos More advances on the mRNA vaccine front this week as both Pfizer and Moderna move forward on new viral targets for future vaccines. Pfizer is turning its focus to...
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What makes an mRNA vaccine so effective against severe COVID-19?
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE The first two vaccines created with mRNA vaccine technology — the Pfizer/BioNTech and Moderna COVID-19 vaccines — are arguably two of the most effective COVID vaccines developed to date. In clinical trials, both were more than 90% effective at preventing symptomatic infection, easily surpassing the 50% threshold the Food and...
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