n January 10, Chinese researchers posted the novel coronavirus’ RNA sequence on a preprint server. Immediately, scientists who study genetic vaccines turned their efforts to the emerging pathogen that causes coronavirus disease 2019 (COVID-19). They knew that rapid response genetic platforms could shave precious weeks to months off development, crucial during a pandemic.\ They were...
Tag: <span>mRNA</span>
A surprising protein player in diabetes
by Okinawa Institute of Science and Technology A protein that’s common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University (OIST) and Riken Center of Integrative Medical Sciences. Called CNOT3, this protein was found...
Fitness in Humans Acts to Reduce Inflammation, But Does Not Reduce the Burden of Cellular Senescence in Muscle Tissue
This news or article is intended for readers with certain scientific or professional knowledge in the field. Fitness produced by training is here shown to correlate with reduced inflammatory signaling, but has no effect on the burden of senescent cells in old muscle tissue. This is interesting, as the accumulation of senescent cells with age...
Experimental COVID-19 vaccine safe, generates immune response
An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online in The New England Journal of Medicine. The ongoing Phase 1 trial is supported by the National Institute of Allergy...
Five things you need to know about: mRNA vaccines
The race for a vaccine against the novel coronavirus, or SARS-CoV-2, is on, with 54 different vaccines under development, two of which are already being tested in humans, according to the World Health Organization. And among the different candidates is a new player on the scene – mRNA vaccines. According to Prof. Bekeredjian-Ding, an approved...
Five things you need to know about: mRNA vaccines
The race for a vaccine against the novel coronavirus, or SARS-CoV-2, is on, with 54 different vaccines under development, two of which are already being tested in humans, according to the World Health Organization. And among the different candidates is a new player on the scene – mRNA vaccines. One mRNA vaccine developed by US...
What the phase 1 trials of the first COVID-19 vaccine really mean
Made from viral proteins, Moderna’s COVID-19 vaccine is composed of synthetic viral mRNA. These molecules are injected into people and cellular protein-making machines, called ribosomes, read and translate the mRNA. It’s these proteins that then trigger an immune response. Credit: The Conversation, CC BY-SA Early morning on May 18, Moderna, a biotechnology company, revealed the...
Opinion: The Central Dogma of Mitochondrial Genetics Needs Rewriting
The recent discovery of 17 people who have inherited maternal and paternal lines of mitochondrial DNA has major ramifications for medical and ancestry research. Until last month, it was generally believed that mitochondria and their DNA are exclusively maternally inherited in humans. In a provocative report in PNAS, scientists identified 17 people from three unrelated...