by University of Exeter Credit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start effective treatments. Optic neuritis is a condition that affects people of all ages, but especially young adults, usually manifesting in blurred vision and sometimes...
by Elana Gotkine For patients with relapsing multiple sclerosis, the anti-CD40L monoclonal antibody frexalimab has a favorable effect on the number of new gadolinium-enhancing T1-weighted lesions, according to a study published in the Feb. 15 issue of the New England Journal of Medicine.Patrick Vermersch, M.D., Ph.D., from the University of Lille in France, and colleagues...
by University of Texas Health Science Center at Houston Credit: CC0 Public DomainThe body’s immune response to Epstein-Barr virus (EBV) may play a role in causing damage in people with multiple sclerosis, according to a new study led by University of Texas Health Houston. EBV infection has long been associated with multiple sclerosis, but how the...
by Claes Björnberg, Umea University Credit: Pixabay/CC0 Public Domain Many risk factors for multiple sclerosis (MS), which causes damage to the central nervous system, have been identified. However, it is still unknown why the disease occurs. In recent years, the herpesvirus Epstein-Barr virus (EBV) has been established as the leading risk factor. “Over 90% of the...
by Erik Robinson, Oregon Health & Science University Credit: CC0 Public Domain New research from Oregon Health & Science University suggests that people with multiple sclerosis, or MS, could benefit from a low-fat diet to improve the fatigue that’s a debilitating, and often-underappreciated, symptom of the condition. The study, published in the Multiple Sclerosis Journal, is...
by Lori Solomon Patients report that a ketogenic diet (KD) improves multiple sclerosis (MS) symptoms, according to a study published in the August issue of Clinical Nutrition. Emma Wetmore, from University of Virginia in Charlottesville, and colleagues evaluated patient perceptions of the KD. The analysis included three-month follow-up from 52 participants with relapsing MS previously...
BRIGHAM AND WOMEN’S HOSPITAL Brigham researchers are working on a new approach to target autoimmunity in the brain leverages designer bacteria to make treatment safer and more effective Researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, have designed a probiotic to suppress autoimmunity in the brain, which occurs when the immune system attacks...
by Emily Moskal, Stanford University Imaging approach for the detection of activated peripheral CNS-infiltrating myeloid cells. Peripheral myeloid cells (monocytes, macrophages, neutrophils, and dendritic cells) are recruited to the central nervous system (CNS) during multiple sclerosis (MS). Peripheral myeloid cells, in addition to brain resident microglia, are associated with CNS MS lesions and are fundamental to...
UNIVERSITÄT LEIPZIG IMAGE: THE IMAGE SERIES SHOWS CROSS-SECTIONAL ELECTRON MICROGRAPHS OF INDIVIDUAL NERVE FIBERS IN MS BRAIN BIOPSIES. AXONS SHEATHED WITH MYELIN (BLACK RINGS) CAN BE SEEN, SHOWING INCREASINGLY SEVERE DAMAGE FROM 1 TO 8. THE SPECTRUM RANGES FROM ACCUMULATION OF INDIVIDUAL CELLULAR COMPONENTS IN OTHERWISE STILL BRIGHT, INTACT AXONS (1) TO ADVANCED DEGENERATION IN...
Nancy A. Melville June 14, 2023 In the ongoing absence of a reliable biomarker for multiple sclerosis (MS), misdiagnosis is a common, and persistent, problem that potentially puts patients at prolonged and unnecessary risk. Experts warn that false-negative diagnoses cause treatment delays, while false-positive diagnoses run the risk for potential harm from needless treatment. Dr Patricia Coyle “MS has...
