by Instituto de Medicina Molecular The microtubule network (green) re-organizes at the muscle lesion and attracts myonuclei. Crédits: William Roman, iMM. Credit: William Roman, iMM. Muscle is known to regenerate through a complex process that involves several steps and depends on stem cells. Now, a new study led by researchers at the Instituto de Medicina...
by Northwestern University Muscle sarcomeres (consecutive green lines), the smallest functional unit of muscle, from inside a living human. Credit: Northwestern University After suffering a stroke, patients often are unable to use the arm on their affected side. Sometimes, they end up holding it close to their body, with the elbow flexed. In a new study,...
by University of Bonn Heart of a healthy (left) and a diseased mouse (cross-sections). Connective tissue inclusions (right, red) make the diseased heart less efficient. Credit: Kenichi Kimura/UKB An international team of researchers led by the University of Bonn has identified the cause of rare, severe muscle disease. According to these findings, a single spontaneously occurring...
by Libby Richards, The Conversation Credit: Unsplash/CC0 Public Domain Millions have rolled up their sleeves for the COVID-19 vaccine, but why haven’t they rolled up their pants legs instead? Why do we get most shots in our arms? As an associate professor of nursing with a background in public health, and as a mother of two curious kids, I...
Two new evidence reviews related to acute musculoskeletal injuries like strains and sprains suggest other forms of treatments are as effective as opioids and have less risk of harms to patients. The details of the systematic reviews and meta-analyses, led by McMaster, were published August 17 in the Annals of Internal Medicine. The first article...
THE PHYSIOLOGICAL SOCIETY New research published today in The Journal of Physiology shows that nitrate improves function in the diaphragm, the muscle involved in coughing and breathing, by improving power. The study done in old mice, if replicated in humans, could provide a strategy for helping elderly people clear the lungs more effectively and avoid...
Enhancement of motor function and muscle strength in aged mice by enhancing formation of neuromuscular junctions THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO THE THERAPEUTIC ADMINISTRATION OF AAV-D7, A VIRAL VECTOR CARRYING THE HUMAN DOK7 GENE, ENHANCES NMJ FORMATION AND INNERVATION TOGETHER WITH MOTOR FUNCTION AND MUSCLE STRENGTH IN AGED MICE (?2 YEARS…view...
Therapeutic manipulations of these cells hold promise for promoting muscle injury repair and improving outcomes for individuals with muscular dystrophy (Boston)– Although macrophages (cells involved in the detection and destruction of bacteria and other harmful organisms as well as dead cells) are classified as immune cells functioning in the activation and resolution of tissue inflammation,...
Loss of a specific enzyme increases fat metabolism and exercise endurance in mice. Sugars and fats are the primary fuels that power every cell, tissue, and organ. For most cells, sugar is the energy source of choice, but when nutrients are scarce, such as during starvation or extreme exertion, cells will switch to breaking down...
Experts document progress made through rehabilitation interventions that improves quality of life Experts document progress made through rehabilitation interventions that improves quality of life for patients with cerebral palsy, in this special issue of the Journal of Pediatric Rehabilitation Medicine Amsterdam, NL, August 3, 2020 – Cerebral palsy (CP) is one of the most common...
