NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY “Many millions of elderly people worldwide suffer from sarcopenia, a disease that is characterized by muscle wasting. A large proportion become so frail that they can no longer exercise,” says Jose Bianco Moreira, a researcher at NTNU, the Norwegian University of Science and Technology. “Gene therapy is the most...
Tag: <span>Muscle loss</span>
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Researchers identify a way to reverse high blood sugar and muscle loss
by Monash University Credit: CC0 Public Domain A study by Monash University has uncovered that liver metabolism is disrupted in people with obesity-related type 2 diabetes, which contributes to high blood sugar and muscle loss—also known as skeletal muscle atrophy. Using human trials as well as mouse models, collaborative research led by Dr. Adam Rose at...
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A new treatment concept for age-related decline in motor function
Enhancement of motor function and muscle strength in aged mice by enhancing formation of neuromuscular junctions THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO THE THERAPEUTIC ADMINISTRATION OF AAV-D7, A VIRAL VECTOR CARRYING THE HUMAN DOK7 GENE, ENHANCES NMJ FORMATION AND INNERVATION TOGETHER WITH MOTOR FUNCTION AND MUSCLE STRENGTH IN AGED MICE (?2 YEARS…view...
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Researchers identify therapeutic targets to prevent cancer-associated muscle loss
by Rockefeller University Press Researchers at the University of Nebraska Medical Center have identified a key cell signaling pathway that drives the devastating muscle loss, or cachexia, suffered by many cancer patients. The study, which will be published May 22 in the Journal of Experimental Medicine, suggests that targeting this pathway with a drug already...
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New treatment hope for those affected by muscle loss
by Wendy Davidson, University of Aberdeen New research from the University of Aberdeen has identified the genes responsible for muscle mass These findings may identify those most at risk from muscle loss as they get older and identifying these genes may unlock the potential for targeted drug therapies that could prevent further muscle loss. Published...
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How diabetes causes muscle loss
Diabetes mellitus is associated with various health problems including decline in skeletal muscle mass. A research group led by Professor Wataru Ogawa at the Kobe University Graduate School of Medicine revealed that elevation of blood sugar levels leads to muscle atrophy and that two proteins, WWP1 and KLF15, play key roles in this phenomenon. These...
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Promising new therapy spares muscle loss in Duchenne muscular dystrophy
A promising therapy for Duchenne muscular dystrophy (DMD) developed by University at Buffalo researchers is moving closer to use in humans. The peptide the new drug is based on was originally found in the venom produced by the type of tarantula that Sachs is holding here. Credit: University at Buffalo Published in July in Neuromuscular Disorders, the new UB research demonstrates that the novel...