by University of Minnesota About one in 8,000 people have facioscapulohumeral muscular dystrophy, according to a 2014 study, which is relatively common in the world of genetic diseases. New University of Minnesota Medical School research identifies an inhibitor that protects cells from toxic effects associated with this disease in cells and mice. Facioscapulohumeral muscular dystrophy...
Tag: <span>muscular dystrophy</span>
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Researchers overcome hurdle in CRISPR gene editing for muscular dystrophy
The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be used to effectively treat long-term, chronic conditions. A research team led by Dongsheng Duan, Ph.D., at the University of Missouri School of Medicine has identified and overcome a barrier in CRISPR gene editing...
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Researchers give new insight to muscular dystrophy patients
New research by University of Minnesota scientists has revealed the three-dimensional structure of the DUX4 protein, which is responsible for the disease, facioscapulohumeral muscular dystrophy (FSHD). Unlike the majority of genetic diseases, FSHD is not caused by a protein that is missing or not functioning properly. Rather it is caused when a functioning, normal, protein...
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Tamoxifen and raloxifene slow down the progression of muscular dystrophy
Long-term treatment with selective estrogen receptor modulators (SERMs) improves muscle, respiratory, and skeletal function without weakening bone in new mouse studies, according to a new report in The American Journal of Pathology Philadelphia, March 20, 2018 – Steroids are currently the only available treatment to reduce the repetitive cycles of inflammation and disease progression associated...
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Scientists discover ‘internal clock’ inside human cells – paving the way to understanding diseases like muscular dystrophy and cancer
Scientists have found first ‘physical’ measure of a cell’s life stage Method will help researchers study ongoing changes in cells Findings could shed light on muscular dystrophy and cardiomyopathy Researchers have discovered the ‘internal clock’ of cells – breaking new ground to understand how diseases take hold of the body. Previously, the biological clock we...