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Discovery offers insight for development of cancer therapies targeting mutant p53
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Discovery offers insight for development of cancer therapies targeting mutant p53

by  Vanderbilt University Medical Center Credit: CC0 Public Domain The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation. However, much remains to be learned about various mutations that lead to a “loss of...