More accurate detection of a specific molecular marker in leukemic cells will help assess measurable residual disease and guide treatment decisions, improving patient outcomes, report investigators in The Journal of Molecular DiagnosticsPeer-Reviewed Publication ELSEVIER Philadelphia, November 13, 2023 – A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML)...
Tag: <span>myeloid leukemia</span>
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Novel therapeutic target for acute myeloid leukemia
by Melissa Rohman, Northwestern University Credit: Unsplash/CC0 Public Domain Northwestern Medicine investigators have discovered the mechanisms by which a particular protein promotes cancer cell proliferation and survival in acute myeloid leukemia (AML), according to a Northwestern Medicine study published in Blood. The findings suggest that PRL2, a protein tyrosine phosphatase, may be a novel therapeutic target for AML, according...
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Breakthrough in precision medicine for the treatment of acute myeloid leukemia
by Karolinska Institutet Credit: Journal of Internal Medicine Researchers at Karolinska Institutet, among others, have studied the benefit of adding an established drug as a novel targeted therapy in the treatment of acute myeloid leukemia (AML). The results suggest that the drug hydroxyurea can increase treatment efficacy at a relatively low cost. The research, which was published...
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New drug combination shows promise in treating acute myeloid leukemia
by Peter MacCallum Cancer Centre Treatment with a histone deacetylase inhibitor induces production of interferon by immune cells, which causes differentiation of leukaemia cells into normal blood cells and ultimately their death (differentiated cells are marked with an arrow). Credit: Peter MacCallum Cancer Centre Research led by Peter Mac and published in Cancer Discovery has found a...
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Global trial reveals life saving drug for acute myeloid leukemia
by Monash University Bone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: Wikipedia A landmark paper published today in the New England Journal of Medicine describes the results from a global trial across 148 sites in 23 countries, showing a 30 percent improvement in survival in patients with acute myeloid leukemia (AML). The Phase...
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Experimental, precision strategy targets unique cancer protein found in certain acute myeloid leukemia cases
Lab study shows promise of aiming genetically engineered T-cell therapy at a gene fusion. Precision immunotherapies that aim the power of the body’s soldier cells at cancer have revolutionized the care of certain types of leukemia. But not all types — yet. New research by a team from Fred Hutchinson Cancer Research Center is helping...