Lehigh University bioengineering researcher Anand Ramamurthi leads team developing minimally invasive techniques to repair and regenerate tissue using actively targeted, drug-releasing nanoparticlesPeer-Reviewed Publication LEHIGH UNIVERSITY ANAND RAMAMURTHI IS P.C. ROSSIN PROFESSOR AND CHAIR OF THE DEPARTMENT OF BIOENGINEERING AT LEHIGH UNIVERSITY, WHERE HE LEADS THE RAMAMURTHI LAB FOR MATRIX ENGINEERING.CREDIT: DOUGLAS BENEDICT/ACADEMIC IMAGE FOR LEHIGH...
by SINTEF Graphical abstract. Credit: Advanced Drug Delivery Reviews (2022). DOI: 10.1016/j.addr.2022.114528 The fact that our immune systems capture and destroy nanoparticles and the drugs they carry has been a problem in the field of nanomedicine for some time. But, in the fight against cancer, researchers are now attempting to exploit this problem to their advantage. Researchers around the world are...
by Anna Megdell, University of Michigan Human metastatic breast cancer in the lymph nodes. Credit: National Cancer Institute Research from the University of Michigan Rogel Cancer Center could provide a new approach to treating an aggressive form of breast cancer. A study led by Duxin Sun, Ph.D., found that targeting the immune microenvironment in lymph nodes and...
Research from the University of Michigan Rogel Cancer Center could provide a new approach to treating an aggressive form of breast cancer. A study led by Duxin Sun, Ph.D., found that targeting the immune microenvironment in lymph nodes and tumors simultaneously led to long-term tumor remission in mice models of metastatic triple-negative breast cancer. Further, using nanoparticles to deliver these...
CHINESE ACADEMY OF SCIENCES HEADQUARTERS IMAGE: CD71 EXPRESSION ON LEUKEMIA CELLS, AS@FN CONSTRUCTION, AND TARGETING ABILITY ANALYSIS CREDIT: IPE Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences, Peking University, and Zhujiang Hospital of Southern Medical University have developed a ferritin (Fn)-based nanomedicine for targeted delivery of arsenic (As) and...
MICHIGAN STATE UNIVERSITY EAST LANSING, Mich. – An international team of researchers led by Michigan State University’s Morteza Mahmoudi has developed a new method to better understand how nanomedicines — emerging diagnostics and therapies that are very small yet very intricate — interact with patients’ biomolecules. Medicines based on nanoscopic particles have the promise to be more...
THE KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KAIST) CREDIT: PROFESSOR JI-HO PARK, KAIST Physicochemical cargo-switching nanoparticles (CSNP) designed by KAIST can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and inflammation. The CSNP-based combination drug delivery therapy was proved to exert cholesterol-lowering, anti-inflammatory,...
Living cells inside the body could be placed under surveillance–their location and migration noninvasively tracked in real time over many days–using a new method developed by researchers at KAUST. The technique uses magnetic core-shell iron nanowires as nontoxic contrast agents, which can be implanted into live cells, lighting up those cells’ location inside a living...
by Greg Weatherford, Virginia Commonwealth University Someday, hundreds of millions of vaccinations against the coronavirus that causes COVID-19 could show up in people’s mailboxes and be applied as simply as slapping on a Band-Aid. That’s the vision of Guizhi “Julian” Zhu, Ph.D., at the Virginia Commonwealth University School of Pharmacy. Zhu, an assistant professor in...
Scientists from NUST MISIS learn how to safely excrete nanomedicine NATIONAL UNIVERSITY OF SCIENCE AND TECHNOLOGY MISIS Scientists at the National University of Science and Technology “MISIS” (NUST MISIS) have identified a new mechanism for removing magnetic nanoparticles through the kidneys, which will help to create more effective and safe drugs. The results of the...
