November 01, 2023 by William Weir Using nanoparticles administered directly into the cerebrospinal fluid (CSF), a research team has developed a treatment that may overcome significant challenges in treating a particularly deadly brain cancer. The researchers, led by professors Mark Saltzman, PhD, and Ranjit Bindra, MD, PhD, administered to mice with medulloblastoma a treatment that...
by Yale University Credit: Yale University A team of researchers has developed an inhalable vaccine that successfully protects against the COVID virus. It also opens the door to delivering other messenger RNA (mRNA) therapeutics for gene replacement therapy and other treatments in the lungs. Results of the study, led by Prof. Mark Saltzman, are published in Science...
Posted 2 days ago In collaboration with Astra Zeneca, new research from Cardiff University used artificial intelligence to create microscopic nanoparticles that can effectively transport medicines to target and treat diseased cells precisely. Pills, medications in hand – illustrative photo. Modern medications are increasingly associated with the use of treatment-delivering nanoparticles. Image credit: Kateryna Hliznitsova via...
MARCH 27TH, 2023 CONN HASTINGSMEDICINE, NANOMEDICINE, NEWS, ONCOLOGY, SURGERY Researchers at the Georgia Institute of Technology have developed a nanotechnological solution for lymphedema, a failure of the lymphatic system that results in uncomfortable and irreversible fluid retention. Previous research efforts have focused on trying to grow new lymphatic vessels, but these researchers have taken a different approach, and instead engineered...
MEMORIAL SLOAN KETTERING CANCER CENTER • The blood-brain barrier prevents most drugs from reaching brain tumors.• A new method using nanoparticles transported drugs across this barrier in mice.• The nanoparticles target a protein on tumor blood vessel cells called P-selectin.• The nanoparticles improved the treatment in a model of aggressive pediatric brain cancer Brain tumors...
by Trinity College Dublin Graphical Abstract. Credit: Cell Reports Medicine (2023). DOI: 10.1016/j.xcrm.2022.100899 Scientists have discovered there is a “Goldilocks” effect in identifying the size of a “vaccine adjuvant” that can trigger strong immune responses and, as an example, have shown that a safe, biodegradable adjuvant can boost the action of cancer-killing cells—if the particles are the...
By Michael Irving December 04, 2022 A new study in mice has shown promise in preventing arthritis Depositphotos Autoimmune diseases are a common health problem, and while system-wide immune suppression can help relieve symptoms, this can cause other complications. In a new study, scientists at Scripps Research developed nanoparticles that can selectively target problematic immune...
XI’AN JIAOTONG-LIVERPOOL UNIVERSITY IMAGE: RESEARCHERS AT XI’AN JIAOTONG-LIVERPOOL UNIVERSITY HAVE SHOWN THAT BRAIN STIMULATION CAN BE ENHANCED BY NON-INVASIVELY DELIVERED NANOPARTICLES. THIS CAN AID RECOVERY AFTER ISCHEMIC STROKE IN AN ANIMAL MODEL. CREDIT: PUBLIC DOMAIN In a recent study, researchers from Xi’an Jiaotong-Liverpool University and other universities in China have reported that brain stimulation combined...
URAL FEDERAL UNIVERSITY IMAGE: THE RESEARCH IS LED BY PROFESSOR URFU DMITRI ALEXANDROV. CREDIT: URFU Physicists and mathematicians from the Ural Federal University (UrFU) have created a complex mathematical model that calculates the distribution of nanoparticles (in particular, viruses) in living cells. The mathematical model helps finding how the nanoparticles cluster (merge into a single...
By Dr. Priyom Bose, Ph.D.Sep 7 2022 Reviewed by Danielle Ellis, B.Sc. The blood-brain barrier (BBB) prevents the passage of foreign substances from the blood to the brain’s extracellular fluid. Several drugs that permeate through the BBB are compromised, and only an insufficient amount reaches the targeted tissues. Nanoparticle-based systems present an excellent opportunity to...
