The findings of a large-scale screen could help researchers design nanoparticles that target specific types of cancer. Using nanoparticles to deliver cancer drugs offers a way to hit tumors with large doses of drugs while avoiding the harmful side effects that often come with chemotherapy. However, only a handful of nanoparticle-based cancer drugs have been FDA-approved. A...
Tag: <span>nanoparticles</span>
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Engineers develop nanoparticles that cross the blood-brain barrier
Tested using a new brain tissue model, the particles may be able to deliver chemotherapy drugs for glioblastoma. There are currently few good treatment options for glioblastoma, an aggressive type of brain cancer with a high fatality rate. One reason that the disease is so difficult to treat is that most chemotherapy drugs can’t penetrate...
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Nanobiotics: Model predicts how nanoparticles interact with proteins
Nanoengineered drugs that stop harmful bacteria and viruses could be on the horizon. With antibiotic-resistant infections on the rise and a continually morphing pandemic virus, it’s easy to see why researchers want to be able to design engineered nanoparticles that can shut down these infections. A new machine learning model that predicts interactions between nanoparticles...
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Technology Org logo SCIENCE & TECHNOLOGY NEWS Nanoparticles prove effective against the yellow fever mosquito
Before being accidentally introduced to the New World by the 16th-century slave trade, the yellow fever mosquito was a species native only to Africa. Highly adaptable, it has since become an invasive species in North America. Still, researchers at The Ohio State University may have found a way to squash the pesky population in its juvenile stages....
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Newly developed nanoparticles show promise for locating, removing endometriosis lesions
by Steve Lundeberg, Oregon State University Credit: Pixabay/CC0 Public Domain Scientists have developed a new nanotechnology approach for locating and removing the painful and dangerous lesions associated with endometriosis, a common gynecological condition in women of childbearing age. The research led by Oleh Taratula of the Oregon State University College of Pharmacy and Ov Slayden...
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“Amazing” Nanoparticles from Maize: A Potent and Economical Anti-Cancer Therapeutic
Nanomaterials have revolutionized the world of cancer therapy, and plant-derived nanoparticles have the added advantage of being cost-effective and easy to mass produce. Researchers from Tokyo University of Science have recently developed novel corn-derived bionanoparticles for targeting cancer cells directly, via an immune mechanism. The results are encouraging, and the technique has demonstrated efficacy in treating...
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Intranasal flu vaccine with nanoparticles offers robust protection, researchers find
by Georgia State University Credit: Pixabay/CC0 Public Domain An influenza vaccine administered through the nose and constructed with nanoparticles that enhance immune response offers strong protection against different influenza virus strains, according to researchers in the Institute for Biomedical Sciences at Georgia State University. The intranasal vaccine contributed to multifaceted immune responses, leading to robust cross protection...
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Protein Coating Protects Nanoparticles from Immune Attack
JANUARY 17TH, 2022 CONN HASTINGS MEDICINE, NANOMEDICINE Researchers at the University of Pennsylvania School of Medicine have created a new coating for nanoparticles that can help to protect them from attacks by the immune system. The approach, which uses naturally occurring proteins that can inhibit the complement system, can significantly reduce immune destruction of nanoparticles, meaning that more...
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Polymer-coated nanoparticles to promote drug delivery to the brain
INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE – INRS IMAGE: PROFESSOR CHARLES RAMASSAMY AND JEAN-MICHEL RABANEL ANALYZING NANOPARTICLES ON THE NANOSIGHT NS 300, EQUIPMENT OBTAINED THANKS TO THE GENEROSITY OF THE CHARRON FAMILY THROUGH THE ARMAND-FRAPPIER FOUNDATION AS PART OF THE LOUISE & ANDRÉ CHARRON RESEARCH CHAIR ON THE ALZHEIMER’S DISEASE. CREDIT: INRS Treating diseases such...
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Nanoparticles create heat from light to manipulate electrical activity in neurons
Nanomaterials have been used in a variety of emerging applications, such as in targeted pharmaceuticals or to bolster other materials and products such as sensors and energy harvesting and storage devices. A team in the McKelvey School of Engineering at Washington University in St. Louis is using nanoparticles as heaters to manipulate the electrical activity...