by Latrobe University Thymic cortical T cell deletion induced by a CDR3 cysteine. TCR-retrogenic mice expressing the 6218 or 6218αC TCR were made as described in Fig. 1, except that all recipients were male B6 mice (n = 4 for 6218; n = 4 for 6218αC). TCR-retrogenic mice were analyzed 5 weeks after BM transfer at 99-138 days of age....
by Anna Megdell, University of Michigan Graphical abstract. Credit: Cancer Cell (2022). DOI: 10.1016/j.ccell.2022.02.003 Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with...
