by Nagoya University Under normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functional machinery is impaired, the splicing ratio of MAPT exon 10+/exon 10- is increased, which in turn results in an increased 4R-Tau/3R-Tau ratio. The findings...
As COVID-19 continues to ravage global populations, the world is singularly focused on finding ways to battle the novel coronavirus. That includes the UC Santa Barbara’s Solid State Lighting & Energy Electronics Center (SSLEEC) and member companies. Researchers there are developing ultraviolet LEDs that have the ability to decontaminate surfaces—and potentially air and water—that have...
Growing neural stem cells is a complicated process that has the potential to result in the unintended production of cancer cells. In large part this is due to the addition of growth factors to the culture mix, which can result in indiscriminate cellular multiplication. Now researchers from the Hong Kong Baptist University have developed a way of...
Since scientists began studying the brain, they have asked whether the biology they observed can really be tied to external behaviors. Researchers are building a substantial understanding of the biophysical, molecular, and cellular interactions of neurons, but directly relating those interactions to outward behaviors is an ongoing challenge in the field. “The biophysical properties of...
