Tag: <span>Neuroactive steroids</span>

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Neuroactive steroids may induce prolonged antidepressant effects by altering brain states

Researchers find a mechanism that may explain the long-lasting effects of allopregnanolone, a neuroactive steroid used therapeutically to treat postpartum depression. By recording electrical activity in the brain, the researchers found that allopregnanolone changes how neurons communicate in the basolateral amygdala, a region important for mood and emotion regulation. Local application of the drug in the basolateral amygdala...