UNIVERSITY OF NORTH CAROLINA HEALTH CARE CHAPEL HILL, NC – A newly developed immunotherapy that simultaneously uses modified immune-fighting cells to home in on and attack two antigens, or foreign substances, on cancer cells was highly effective in mice implanted with human neuroblastoma tissue, report researchers from the UNC Lineberger Comprehensive Cancer Center and the UNC School...
Tag: <span>neuroblastoma</span>
Post
Natural ‘brake’ against malignant neuroblastoma turns tumors benign
by St. Anna Children’s Cancer Research Institute Tamara Weiss, PhD, and Sabine Taschner-Mandl, PhD, discover that the uncontrolled growth of neuroblastomas (green tumor cells) is stopped by a signal molecule produced by Schwann cells (magenta). Credit: Photo: Sabine Taschner-Mandl, PhD, and Tamara Weiss, PhDCopyright: St. Anna Children’s Cancer Research InstituteImage: Immunofluorescence image of Schwann cells (magenta) and...
Post
COVID-19: Stem Cell Therapy Shows 83% Survival of Coronavirus Patients, Study Found
By Tiziana Celine Tech Times Doctors are hoping stem cell therapy may be a weapon in the fight against coronavirus. Regenerative medicine employer Mesoblast introduced a 300-person trial on Friday, Apr. 24, to decide whether or not stem cell treatments will work in COVID-19 patients tormented by severe lung inflammation. The treatments had been intravenous...
Post
Antibody-drug conjugate shows efficacy against cell surface protein in Neuroblastoma
Physician-scientists in the Cancer Center at Children’s Hospital of Philadelphia (CHOP) have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, effectively killing cancer cells. The researchers published their findings today in Science Translational Medicine. “If there is an ultimate ‘bad guy’ of neuroblastomacell surface...
Post
Neuroblastoma Molecular Analysis Leads to Potential Prognostic Markers
NEW YORK (GenomeWeb) – A team led by researchers at the University of Cologne in Germany has identified telomere maintenance, RAS, and TP53 pathway alterations in neuroblastoma that appear to provide insights into patients’ prognoses. “Our findings may have important implications for the diagnosis and treatment of neuroblastoma patients, which should be validated in future...
Post
Drug combination makes cancer disappear in mice with neuroblastoma
Researchers investigating new treatments for neuroblastoma—one of the most common childhood cancers—have found that a combination of two drugs made tumours disappear in mice, making it more effective than any other drugs tested in these animals. Professor Murray Norris, deputy director of the Children’s Cancer Institute Australia for Medical Research, Sydney, Australia, told the 30th...
Post
Testing a new immunotherapy treatment for neuroblastoma
T cells are important fighters against disease. Immunotherapies are changing the outlook for many cancer patients. Drugs that block cancer cells from deflecting an immune attack are now routinely used to treat advanced skin and kidney cancers, and are showing promise in other types of cancer too. But cancers are complex and diverse – what works...