Cleveland Clinic researchers have discovered a new subtype of multiple sclerosis (MS), providing a better understanding of the individualized nature of the disease. Bruce Trapp, PhD, Cleveland Clinic. Credit: Cleveland Clinic MS has long been characterized as a disease of the brain’s white matter, where immune cells destroy myelin—the fatty protective covering on nerve cells. The destruction...
Tag: <span>neurodegeneration</span>
Post
Genetic tools uncover cause of childhood seizure disorder missed by other methods
UNIVERSITY OF UTAH HEALTH Early childhood seizures result from a rare disease that begin in the first months of life. Researchers at University of Utah Health have developed high-tech tools to uncover the genetic cause of the most difficult to diagnose cases. The results are available online on August 13 in the journal Nature Genomic...
Post
Experts highlight new concepts and approaches to the rehabilitation of stroke
Stroke remains a leading cause of adult disability, and the global burden of stroke continues to grow with devastating consequences for patients, families, and caregivers. In this special issue of NeuroRehabilitation leading international experts on stroke rehabilitation provide theoretical and practical insights into the steps necessary to push beyond merely compensatory training and onto a level of...
Post
The secret sulfate code that lets the bad Tau in
Research uncovers details of how neurodegeneration-related proteins enter cells AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY Vampires can turn humans into vampires, but to enter a human’s house, they must be invited in. Researchers at the UT Southwestern Medical Center, writing in the Journal of Biological Chemistry, have uncovered details of how cells invite inside corrupted...
Post
Simple sugar delays neurodegeneration caused by enzyme deficiency
June 20, 2018, Baylor College of Medicine A new therapeutic approach may one day delay neurodegeneration typical of a disease called mucopolysaccharidoses IIIB (MPS IIIB). Neurodegeneration in this condition results from the abnormal accumulation of essential cellular molecules called mucopolysaccharides. Looking to find alternative therapeutic strategies for this rare genetic disease, a team of researchers investigated...
Post
Neurodegeneration: New cell death mechanism revealed
New research reveals how a dysfunction in the brain’s so-called self-digestion system leads to cell death in neurodegenerative disorders. The newly discovered mechanism may lead to new therapies for conditions such as Parkinson’s and Alzheimer’s disease. When the brain’s ‘housekeeping’ mechanism fails, neurons start degenerating. New research shows how. A healthy brain has a self-cleaning...