JULY 25, 2024 by King’s College London Model of mitochondrial homeostasis and cytoplasmic viscosity during aging. Credit: Aging Cell (2024). DOI: 10.1111/acel.14250A team from King’s College London and collaborators have pinpointed how different areas of the neuron age differently, with a potential knock-on effect on healthy cell function and the development of neurodegenerative conditions. The...
Vascular defects and neuroinflammationUNIVERSITY OF BARCELONA IMAGE: FROM LEFT TO RIGHT, THE EXPERTS PILAR VILLACAMPA, VÍCTOR ARRIBAS AND ELOI MONTAÑEZ, FROM THE FACULTY OF MEDICINE AND HEALTH SCIENCES OF THE UNIVERSITY OF BARCELONA AND IDIBELL. view moreCREDIT: UNIVERSITY OF BARCELONA Defects in the blood vessel network of the central nervous system have been linked to...
By Bhavana Kunkalikar May 22 2023 Reviewed by Benedette Cuffari, M.Sc. In a recent study published in the journal Nature Communications, researchers explore the relationship between gout and neurodegenerative disease susceptibility. Study: Association of gout with brain reserve and vulnerability to neurodegenerative disease. Image Credit: Triff / Shutterstock.com What is gout? Gout, which is often referred to as hyperuricemia, is...
by Arizona State University The illustration shows the cell types and brain regions affected by six different neurodegenerative diseases: Friedreich’s ataxia (purple); Huntington’s disease (blue); frontotemporal dementia (yellow); amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig’s disease (green); Parkinson’s disease (orange); and Alzheimer’s disease (pink). Credit: Shireen Dooling A perplexing...
by Kristine Zengeler, The Conversation Graphical abstract. Credit: Cell (2022). DOI: 10.1016/j.cell.2022.09.030 Many neurodegenerative diseases, or conditions that result from the loss of function or death of brain cells, remain largely untreatable. Most available treatments target just one of the multiple processes that can lead to neurodegeneration, which may not be effective in completely addressing disease symptoms or progress,...
by Public Library of Science Researchers assess hospital-treated infection and risk of neurodegenerative diseases. Created with Adobe Illustrator. Credit: Jiangwei Sun (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) Infections treated with specialty hospital care in early- and mid-life are associated with an increased subsequent risk of Alzheimer’s (AD) and Parkinson’s diseases (PD), but not amyotrophic lateral sclerosis (ALS), according to...
by University of California, San Francisco Credit: Unsplash/CC0 Public Domain Some people are gifted with genes that pack the benefits of slumber into an efficient time window, keeping them peppy on only four or six hours of sleep a night, according to researchers at UC San Francisco. In addition, the scientists said, these “elite sleepers”...
Oregon State University scientists have discovered a new class of potential drug targets for people suffering from neurodegenerative conditions such as Alzheimer’s, Parkinson’s and Lou Gehrig’s disease. The possible targets are oxidized proteins, and researchers in the OSU College of Science are now in pursuit of the best way to attack them. A drug target...
by Oregon State University Kyle Nguyen, left, Maca Franco and Lydia Bastian. Credit: Hannah O’Leary, Oregon State University Oregon State University scientists have discovered a new class of potential drug targets for people suffering from neurodegenerative conditions such as Alzheimer’s, Parkinson’s and Lou Gehrig’s disease. The possible targets are oxidized proteins, and researchers in the...
Two researchers from Skoltech and McGill University have published a review of the promising research field known as structural proteomics in the influential journal Chemical Reviews. This field combines protein chemistry and mass spectrometry, an advanced analytical technique for identifying the chemical composition of substances based on precise mass. The ultimate goal is to resolve the detailed structure of...
