By Dr. Chinta SidharthanJun 13 2023 Reviewed by Benedette Cuffari, M.Sc. In a recent study published in the journal Plants, researchers investigate the composition, antioxidant activity, flavonoid and polyphenol content, as well as other properties of bergamot fiber powder. The researchers also determined the effect of bergamot fiber on an in vitro neurotoxicity model induced by amyloid beta...
by Justin Jackson, Medical Xpress Differences in regional gray matter volume between participants with gout (n = 1,165) and controls (n = 32,202), as analyzed by voxel-based morphometry. Blue regions represent areas where participants with gout had significantly less gray matter. T statistics are thresholded at a 5% false discovery rate (0.0013 threshold on uncorrected P values). Models adjusted...
by International Society for Stem Cell Research Graphical abstract. Credit: Clive Svendsen, Cedars-Sinai Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, USA Progressive loss of neurons is the underlying cause for a diverse spectrum of severe diseases called neurodegenerative diseases, which include Parkinson’s disease, amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa. While strategies for regenerating...
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE PHILADELPHIA — Penn Medicine researchers have solved a decades old mystery around a key molecule fueling the power plant of cells that could be exploited to find new ways to treat diseases, from neurodegenerative disorders to cancer. Reporting in a new study published today in Nature, researchers from the Department...
by Nagoya University Under normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functional machinery is impaired, the splicing ratio of MAPT exon 10+/exon 10- is increased, which in turn results in an increased 4R-Tau/3R-Tau ratio. The findings...
by German Center for Neurodegenerative Diseases An infection with the coronavirus SARS-CoV-2 can affect multiple organs. With this in mind, researchers of the German Center for Neurodegenerative Diseases (DZNE) and Cornell University in the US have investigated cellular factors that could be significant for an infection. To this end, they analyzed the activity of 28...
by University of Sheffield Scientists have made a breakthrough in understanding how the enteric nervous system forms, which could pave the way for new treatments for neurodegenerative diseases such as Parkinson’s. The findings, published in the journal Stem Cell Reports, pave the way for using stem cells to understand and treat a range of diseases...
by University of California, San Francisco Women with Alzheimer’s live longer than men with the disease, and scientists at UC San Francisco now have evidence from research in both humans and mice that this is because they have genetic protection from the ravages of the disease. By virtue of having a second X chromosome, women...
by Sarah Lichtman, Cedars-Sinai Medical Center A study published today in the journal Nature could help explain why certain people who develop amyotrophic lateral sclerosis (ALS), a deadly neurological disorder also known as Lou Gehrig’s disease, are prone to autoimmune diseases. ALS, which has no known cure, causes progressive degeneration of nerve cells in the...
When our neurons — the principal cells of the brain — die, so do we. Most neurons are created during embryonic development and have no “backup” after birth. Researchers have generally believed that their survival is determined nearly extrinsically, or by outside forces, such as the tissues and cells that neurons supply with nerve cells....
