By Anthoni Oisin, BScReviewed by Danielle Ellis, B.Sc. Neurological disorders and neurodegenerative diseases impact many people. The Lancet published a study estimating that a neurological condition impacts more than one in three people. 1 Neurodegenerative diseases also impact a large part of the population: The World Health Organisation estimates that 55 million people have some...
By Matthew AdamsReviewed by Danielle Ellis, B.Sc. Spatial transcriptomics is a new tool that may prove key to increasing our understanding of tissues and the cellular processes at work in a 3D space. This article describes the basic principles of spatial transcriptomics, alongside its application in neuroscience both cognitively and clinically. Image Credit: PeopleImages.com –...
University of Western Ontario Researchers developed an efficient, non-invasive method to get a clearer picture of the structure and function of the hippocampus, a crucial region in our brain. Credit: Roy Haast/BrainsCAN imageThe hippocampus—a seahorse-shaped region of the brain that plays a particularly important role in cognitive aging and memory function—has been studied as a...
Researchers survey a broadening landscape of studies showing what’s known, and what remains to be found, about the therapeutic potential of noninvasive sensory, electrical, or magnetic stimulation of gamma brain rhythms. Brain stimulation – artistic interpretation. A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility...
A new review surveys a broadening landscape of studies showing what’s known, and what remains to be found, about the therapeutic potential of non-invasive sensory, electrical or magnetic stimulation of gamma brain rhythms Peer-Reviewed Publication PICOWER INSTITUTE AT MIT PICOWER PROFESSOR LI-HUEI TSAI HAS LED A COLLABORATION STUDYING SENSORY STIMULATION OF GAMMA RHYTHMS TO TREAT...
by Université libre de Bruxelles Repurposing Wnt7a ligands into BBB therapeutics.BBB dysfunction has been implicated in the etiology of a large set of CNS disorders. Wnt7a/b ligands, which dominate the neurovascular differentiation cascade during vertebrate development, are here repurposed as safe BBB therapeutics by engineering them into highly specific Gpr124/Reck agonists. [Illustration created with BioRender]....
by Hong Kong Baptist University Professor Ken Yung Kin-lam (right) and Dr Fu Pengfei, Postdoctoral Research Fellow of the Department of Biology of HKBU, find a strong association between PM2.5 and a wide range of neurological disorders. Credit: Hong Kong Baptist University A comprehensive, systematic meta-analysis conducted by HKBU scientists found a significant association between exposure to PM2.5,...
by National Institutes of Health NIH scientists discovered that intense neural conversations thought to underlie learning and memory may be fueled by an energy-sensing feedback loop. Here scientist monitored energy levels in the form of ATP as neurons talked to each other. Our thoughts, feelings, and movements are controlled by billions of neurons talking to each...
An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases. The scientists compared the most common inherited form of amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) with a rarer disease called spinocerebellar ataxia type 36 (SCA36). Both of the diseases are caused by abnormally expanded and...
St. Jude Children’s Research Hospital scientists offer insight into the toxicity at the heart of devastating neurological disorders ST. JUDE CHILDREN’S RESEARCH HOSPITAL St. Jude Children’s Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease. The research suggests possible new approaches to diagnosis and treatment of the lethal disorder. The findings appear online...
