Tag: <span>neurological gene therapy</span>

Home / neurological gene therapy
Researchers develop approach to prevent toxicity tied to neurological gene therapy
Post

Researchers develop approach to prevent toxicity tied to neurological gene therapy

by  Perelman School of Medicine at the University of Pennsylvania Delivering adeno-associated virus (AAV) vectors into the central nervous system (CNS) of nonhuman primates is associated with toxicity of sensory neurons in the dorsal root ganglia (DRG), which conventional immune suppression regimens do not prevent. Hordeaux et al. exploited a specific microRNA (miR183) that is largely...