cby Suzanne Leigh, University of California, San Francisco Credit: Pixabay/CC0 Public Domain An experimental method developed to detect nerve injury in multiple sclerosis (MS) in adults also works for children with MS and other neurological conditions, even when they are symptom-free, according to an international team of researchers. In MS, early intervention with more recently approved...
by Todd Bates, Rutgers University This drug delivery system includes a porous biodegradable platform that can reduce nervous tissue inflammation and may help treat spinal cord injuries and other neurological disorders. A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and...
by University of Rochester Medical Center New research details how the complex set of molecular and fluid dynamics that comprise the glymphatic system—the brain’s unique process of waste removal—are synchronized with the master internal clock that regulates the sleep-wake cycle. These findings suggest that people who rely on sleeping during daytime hours are at greater...
by Melissa Moody, Perelman School of Medicine at the University of Pennsylvania An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein’s buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn...
by Stevens Institute of Technology By detecting subtle differences in the way that Alzheimer’s sufferers use language, researchers at Stevens Institute of Technology have developed an A.I. algorithm that promises to accurately diagnose Alzheimer’s without the need for expensive scans or in-person testing. The software not only can diagnose Alzheimer’s, at negligible cost, with more...
by Rockefeller University Some highly effective medications also happen to be highly mysterious. Such is the case with the antidepressant drugs known as selective serotonin reuptake inhibitors, or SSRIs: They are the most common treatment for major depression and have been around for more than 40 years, yet scientists still do not know exactly how...
People with Parkinson’s disease and some other neurological disorders often suffer from a condition known as freezing of gait. For poorly understood reasons, initiating a step is often a challenge. Patients report a feeling of disassociation between one’s will to move and the legs not responding accordingly. This is both frustrating and can lead to...
by University of Portsmouth Zebrafish in the maze. Credit: University of Portsmouth A test of fish behavior in a maze has shed light on human degenerative conditions, heralding new hope for treatments. Fish swimming through a simple maze has shown ‘exceptional’ potential to improve progress in developing treatments for brain and psychiatric disorders, including Alzheimer’s...
by Baylor College of Medicine cs, pediatrics and neuroscience, and Ralph D. Feigin, M.D. Endowed Chair at Baylor. “When we identified the gene, we learned that mutations can cause the ATXN1 protein to remain in cells longer than normally. This is bad news for neurons as too much ATXN1 leads to their death.” The findings...
by Brittany Uhlorn, University of Arizona The powerful biomolecular NMR spectrometers at the University of Arizona have allowed scientists to gain molecular details of the interaction between RCAN1 and calcineurin, two proteins that have long been implicated in Down syndrome and Alzheimer’s disease. Credit: University of Arizona From the movement of a finger to the...
