Tag: <span>Neuron death</span>

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Silencing of an ALS gene safely delivered to patients in new study
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Silencing of an ALS gene safely delivered to patients in new study

by Jim Fessenden, University of Massachusetts Medical School UMass Medical School and Massachusetts General Hospital are the first to safely treat two research participants with a synthetic microRNA, delivered into the spinal fluid, designed to silence a human disease-causing gene. Details of the treatment, which targeted the mutant SOD1 gene that causes ALS, appear in...

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Neuron death in ALS more complex than previously thought

Brown University researchers have uncovered new clues about the progression of Amyotrophic Lateral Sclerosis (ALS), a surprisingly common disease that causes the death of motor neurons that control voluntary muscles such as those involved in walking, talking, chewing or breathing. A team led by Anne Hart, a professor of neuroscience at Brown, discovered that two...