by Howard Hughes Medical Institute Benchmarking Rastermap on simulated data with multiplexed neural activity. Credit: Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01783-4 Neuroscientists have learned a lot—like which neurons and circuits are associated with different behaviors—by recording the activity of small sets of neurons. But what happens when you record thousands of neurons at one time? Or when you want to figure...
Tag: <span>neuronal activity</span>
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Neuronal activity shapes the development of astrocytes, shows study
by Baylor College of Medicine Researchers at Baylor College of Medicine have unraveled the processes that give astrocytes, the most abundant glial cell in the brain, their special bushy shape, which is fundamental for brain function. They report in the journal Nature that neuronal activity is necessary and sufficient for astrocytes to develop their complex shape, and interrupting this...
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Scientists elucidate how chemogenetic technology highjacks neuronal activity
by University of North Carolina Health Care Credit: University of North Carolina Health Care Understanding of how neuronal activity modulates brain function is a key first step towards creating more effective drugs to treat a variety of neuropsychiatric illnesses, including depression, anxiety, schizophrenia, substance abuse, epilepsy, and others. To both manipulate and understand this basic...
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Scientists identify alterations of neuronal connectivity in the cortex in OCD patients
Obsessive-compulsive disorder (OCD) is characterized by alterations in brain connectivity, i.e., patients present a dysfunction related to the synchronization of activity between different groups of neurons, as evidenced by recent research. In a study published this month in the journal Cerebral Cortex, researchers belonging to three CIBER groups of Mental Health (CIBERSAM) led by Jesús...