by University of Barcelona The study led by the UB, IBMB-CSI, and CIBERNED reveals a decisive mechanism related to neuronal death and motor alterations in the most evolved mammals, which could help fight neurodegenerative diseases. Credit: Science Signaling (2024). DOI: 10.1126/scisignal.abq1007The human brain is an organ that requires 20% to 25% of the energy the body...
by Autonomous University of Barcelona Microglial cells in an affected brain region in untreated diseased animals (left) and the same region in treated animals (right). Credit: Autonomous University of Barcelona Microglia, a type of central nervous system cell, is primarily responsible for neuronal death in Leigh Syndrome and the neurological symptoms related to this mitochondrial...
by The Spanish National Cancer Research Centre Mouse motor neurons, generated from mouse embryonic stem cells exposed (right) or not (left) to ALS-associated peptides (right). As observed in patients, these peptides are toxic and cause neuronal death. Credit: CNIO In amyotrophic lateral sclerosis (ALS), the progressive death of neurons that control body movement leads to paralysis of muscles...
