WEILL CORNELL MEDICINE A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute. In the study, published Aug. 2 in the British Journal of Anaesthesia, the first-in-class drug conceptualized...
Tag: <span>neuropathic pain</span>
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Gene Tiam1 orchestrates the development of chronic neuropathic pain
BAYLOR COLLEGE OF MEDICINE Neuropathy is a type of chronic pain triggered by nerve injury or certain diseases. It affects millions of people worldwide, significantly deteriorating their quality of life. Neuropathy, for example, might emerge from hurting the sciatic nerve on the lower back or the spinal cord, in diseases like rheumatoid arthritis and diabetes...
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Calcium channels regulate neuroinflammation and neuropathic pain
by Melissa Rohman, Northwestern University Image showing microglia in the lumbar spinal cord labeled with the microglial marker IBA1 (in red). The blue stain shows nuclei of cells labeled with a nuclear marker. Credit: Prakirya laboratory Northwestern Medicine investigators have discovered that specific calcium channels help regulate sex differences in the functioning of immune cells...
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DyAnsys Neurostimulation Device Approved for Neuropathic Pain
BY QUINN PHILLIPS | AUGUST 2, 2022 The U.S. Food and Drug Administration (FDA) has approved a neurostimulation device from DyAnsys, Inc., to treat pain related to diabetic peripheral neuropathy, according to a press release from the company. The newly approved device, called First Relief, is what’s known as a PENS (percutaneous electrical neurostimulation) device. That means...
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DyAnsys Neurostimulation Device Approved for Neuropathic Pain
BY QUINN PHILLIPS | JANUARY 1, 1970 The U.S. Food and Drug Administration (FDA) has approved a neurostimulation device from DyAnsys, Inc., to treat pain related to diabetic peripheral neuropathy, according to a press release from the company. The newly approved device, called First Relief, is what’s known as a PENS (percutaneous electrical neurostimulation) device. That means...
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Study reveals most effective drugs for common type of neuropathic pain
by University of Missouri Richard Barohn, MD, is the lead researcher and executive vice chancellor for health affairs at the University of Missouri More than 20 million people in the U.S. suffer neuropathic pain. At least 25% of those cases are classified as unexplained and considered cryptogenic sensory polyneuropathy (CSPN). There is no information to guide...
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Use of pain drug Lyrica common among injecting drug users, study finds
by University of New South Wales The use of pregabalin, a medicine for neuropathic pain, is relatively common among a sample of people who regularly inject drugs (PWID) in Australia, a new study by researchers at the National Drug and Alcohol Research Center (NDARC), UNSW Sydney has found. In a sample of 905 participants from...
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Legal Cannabis hemp oil effectively treats chronic neuropathic pain: study
by University of New Mexico Researchers examine the effectiveness of consuming hemp oil extracted from the whole Cannabis plant using a chronic neuropathic pain animal model. Researchers at The University of New Mexico (UNM) showed that legal Cannabis hemp oil reduced mechanical pain sensitivity 10-fold for several hours in mice with chronic post-operative neuropathic pain....
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Pain, but not as we know it: Neuropathic pain and the immune system
by CNBP There are three main types of pain: nociceptive pain, the type we’re most familiar with, from bee stings and ankle strains to inflammatory arthritis. There’s neuropathic pain, arising from damage to the peripheral nervous system or the brain itself due to disease or injury. Then there are functional pain disorders arising from complex...
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Early prevention of neuropathic pain
by Torsten Arndt, Fraunhofer-Gesellschaft An unpleasant tingling in the hands and feet, numbness, fuzzy and burning sensations—these symptoms may indicate a neuropathy, a disease of the nervous system. If the pain persists for several months, it is referred to as chronic pain. By then, it is very difficult to treat, and the available drugs often...
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