by Ellen Goldbaum, University at Buffalo University at Buffalo researchers who previously discovered how chronic neuropathic pain arises in the brain have now developed a treatment to block it. The research conducted by scientists in the Jacobs School of Medicine and Biomedical Sciences at UB was published online July 31 in the journal Brain, Behavior, and...
Tag: <span>neuropathic pain</span>
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Researchers are testing ultrasound to treat neuropathic pain
by Sarah Meehan, The Baltimore Sun Steroid injections, nerve stimulators and spinal fusions were no match for the chronic pain in Tammy Durfee’s left side—never mind the “searing-hot poker” sensation that would jab her leg without warning. After a decade searching for relief, a four-hour procedure in Baltimore put her pain to rest. Durfee, of Higginsville, Mo., was the...
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A new approach to peripheral nerve injury?
In animal models of a totally crushed peripheral nerve, the damaged axons are broken down, allowing healthy ones to regrow. But humans rarely suffer complete axonal damage. Instead, axons tend to be partially damaged, causing neuropathic pain — a difficult-to-treat, chronic pain associated with nerve trauma, chemotherapy and diabetes. A new study in Cell, led...
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Scientists reveal new avenue for drug treatment in neuropathic pain
New research from King’s College London has revealed a previously undiscovered mechanism of cellular communication, between neurons and immune cells, in neuropathic pain. The authors, who published their findings today in Nature Communications, identified a new method of treating neuropathic pain in mice, which could be more safe and effective than current treatments comprising of opioids...
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Vitamin D deficiency tied to neuropathic pain
(HealthDay)—Vitamin D deficiency may be associated with increased neuropathic pain (NP) in patients with rheumatoid arthritis (RA), according to a study published online Aug. 31 in the International Journal of Rheumatic Diseases. Hilal Yesil, from Afyon Kocatepe University in Turkey, and colleagues used the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire to evaluate NP...
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Review: cannabis may alleviate neuropathic pain
Shannon M. Nugent, Ph.D., from the VA Portland Health Care System and Oregon Health & Science University, and colleagues conducted a systematic review to examine the benefits of plant-based cannabis preparations for treating chronic pain in adults. The researchers found low-strength evidence that cannabis alleviates neuropathic pain based on 27 chronic pain trials; insufficient evidence was found in other pain populations....
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Scientists discover new category of analgesic drugs that may treat neuropathic pain
New research published online in The FASEB Journal suggests that a novel therapeutic target called LPCAT2 may prove effective against pain that is not receptive to the current treatments. This study has also revealed the existence of a platelet alleviating factor (PAF) pain loop, suggesting a possible role for PAF-receptor antagonists. “We hope this finding contributes to...
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