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Serum TDP-43 levels may help identify neuropathological changes associated with frontotemporal dementia
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Serum TDP-43 levels may help identify neuropathological changes associated with frontotemporal dementia

by University of Eastern Finland Serum total TDP-43 concentrations in individual subgroups based on the clinical phenotypes of frontotemporal dementia (FTD), in the total FTD group including all of the phenotypes, and in healthy controls (HC). The values were obtained using natural logarithmic transformation. Black horizontal lines indicate group median and interquartile ranges. p-values are...

Aluminum is intricately associated with the neuropathology of familial Alzheimer’s disease
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Aluminum is intricately associated with the neuropathology of familial Alzheimer’s disease

IOS PRESS IMAGE: THE IMAGE SHOWS ALUMINUM (ORANGE) IN A NEURON IN A DONOR’S BRAIN TISSUE WITH FAMILIAL ALZHEIMER’S DISEASE. THE SAME NEURON REVEALED POSITIVE IMMUNOSTAINING (BROWN) FOR PHOSPHORYLATED TAU (PTAU). MERGING THESE IMAGES SHOWED THAT ALUMINIUM AND pTau ARE CO-LOCATE DIN THE SAME CELL. CREDIT: DR. MOLD Amsterdam, April 9, 2021 — This study builds upon...