Botox is a muscle-relaxing toxin used cosmetically and for other purposes Researchers mined a US database of side-effects experienced from medications Patients given Botox were compared with those using alternative treatments The team found that the former were 40–88% less likely to report depression Further tests will be needed to confirm if and how Botox...
By Rich Haridy July 15, 2020 New research is illustrating the differences in toxic protein accumulations in the brains of older subjects suffering cognitive decline compared to older subjects with unexpectedly strong cognitive abilities. An image compiled from PET scans of these so-called “super-agers” has won Image of the Year from the Society of Nuclear...
by Institute for Research in Biomedicine (IRB Barcelona) The amyloid precursor protein (APP) is inserted into the cell membrane of neurons. After sequential cleavage by β- and ?-secretases, the Aβ protein (in green) is released.The membrane oligomers are formed by 4 or 8 copies of the Aβ protein. The physicochemical properties of the edges of...
by Georgetown University Medical Center A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer’s disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy. The results...
University of South Florida study suggests a new approach to inhibit the buildup of brain damaging tau tangles associated with frontotemporal dementia and Alzheimer’s disease UNIVERSITY OF SOUTH FLORIDA (USF HEALTH) TAMPA, Fla. (Feb. 17, 2020) — The protein β-arrestin-2 increases the accumulation of neurotoxic tau tangles, a cause several forms of dementia, by interfering...
