JULY 2, 2024 by Lori Solomon The mean cost of developing a new drug for the U.S. market is estimated to be $879.3 million when both drug development failure and capital costs are considered, according to a study published online June 28 in JAMA Network Open. Aylin Sertkaya, Ph.D., from Eastern Research Group Inc., in...
by Morgan Duerden, University of North Carolina School of Medicine Credit: Pixabay/CC0 Public DomainEosinophilic esophagitis (EoE) is an allergic inflammatory disorder that affects the esophagus, causing distressing symptoms such as difficulty swallowing in adolescents and adults, and vomiting and abdominal pain in children. Evan Dellon, MD, MPH, a gastroenterologist at UNC Health and professor of medicine...
By Paul McClure A novel drug prevented eye and kidney complications in diabetic mice Depositphotos Researchers have identified a novel inhibitor drug that, when given to mice, prevented both eye and kidney complications commonly seen in diabetics. With the potential for one medication to treat two complications, further research is being done to advance the drug...
Peer-Reviewed Publication INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) Barcelona, 30 January 2024 – Protein degraders, a novel approach in drug discovery, show promise to tackle diseases previously thought to be untreatable. Unlike traditional drugs that block specific protein functions, degraders alter the cell’s natural degradation process so that it can remove disease-relevant proteins. However,...
by Anne Trafton, Massachusetts Institute of Technology The cysts that appear in ADPKD cause kidneys to enlarge until they no longer function properly (center image). At the right is a kidney following treatment with the new compound, which has shrunk to a size similar to that of an undiseased kidney (left). Credit: Massachusetts Institute of TechnologyAutosomal...
by Eric Eraso, University of Central Florida Credit: Pixabay/CC0 Public DomainA UCF College of Medicine researcher is developing a new treatment that could slow or even stop cancer cells from spreading. Dr. Otto Phanstiel, a medicinal chemist, has created a compound that literally stops cells from moving and is working with the Mayo Clinic to optimize...
WSOCTV.com News Staff Earlier this month, UNC Health Pardee became the first Western North Carolina hospital to administer a dose of a promising new Alzheimer’s drug, according to our news partners at WLOS in Asheville. ALSO READ: Former WSOC anchor dies after battle with Alzheimer’s disease The new drug is called Lecanemab and works by...
by Ohio State University Medical Center Credit: Unsplash/CC0 Public Domain A new targeted drug, studied by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James), may offer a new treatment option for patients with blood cancers, including chronic lymphocytic leukemia (CLL) and Non-Hodgkin lymphoma (NHL)...
by American College of Physicians Credit: CC0 Public DomainAn animal sedative approved by the FDA, xylazine has now made its way to the illicitly manufacture fentanyl supply, creating new challenges for physicians caring for its victims. Xylazine, an animal sedative that is approved by the U.S. Food and Drug Administration (FDA) for veterinary use only, has...
by eLife Credit: Pixabay/CC0 Public Domain Scientists have found a potential new drug target for untreatable fatty liver disease in humans, according to a study published today in eLife. Their findings, from mice and human liver biopsies, suggest that targeting a receptor found predominantly in the liver could help protect against the build-up of fat, halting...
