Lei Lei Wu News Reporter Stanford scientists have hatched a new type of drug that can turn a cancer promoter into a cancer killer. In a study published in Nature Wednesday, researchers led by Stanford biochemists Nathanael Gray and Jerry Crabtree detailed how they developed a drug that can flip a protein that typically promotes the growth...
Tag: <span>new drug</span>
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New drug may treat rare diseases that make exposure to sunlight painful
by Amy Norton It sounds like the stuff of a vampire novel, but for people with a group of rare genetic disorders, exposure to sunlight can cause excruciating pain. Now, an experimental medication is showing promise for helping them better tolerate the light of day. In an early clinical trial, researchers tested the drug for patients with...
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New Drug to Lower Brain Pressure Could Treat Blinding Headaches
Summary: Exenatide, an injectable peptide currently in phase two clinical trials for treating type 2 diabetes, reduces symptoms of Idiopathic Intercranial Hypertension blinding headaches, a new study reports. Source: University of Birmingham Patients with ‘blinding’ headaches known as Idiopathic Intercranial Hypertension (IIH) could be treated with an injectable peptide used for type 2 diabetes, a new trial...
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EXPLAINER: New drug slows Alzheimer’s but comes with caveats
by LAURAN NEERGAARD and MATTHEW PERRONE This Dec. 21, 2022 image provided by Eisai in January 2023, shows vials and packaging for their medication Leqembi. On Friday, Jan. 6, 2023, U.S. health officials approved Leqembi, a new Alzheimer’s drug that modestly slows the brain-robbing disease. The Food and Drug Administration granted the approval Friday for patients in the early...
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US approves new drug to treat Alzheimer’s disease
by Lucie Aubourg and Chris Lefkow A caretaker helps an elderly resident suffering from Alzheimer’s in a home on the outskirts of Paris. The US Food and Drug Administration on Friday approved a highly anticipated new drug designed to slow cognitive decline in patients in mild and early stages of Alzheimer’s disease. The FDA approval...
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New drug offers hope for people with hand osteoarthritis
by University of Oxford Diagram illustrating the anti-inflammatory role of all-trans retinoic acid (atRA) after cartilage injury. Credit: Science Translational Medicine (2022). DOI: 10.1126/scitranslmed.abm4054 A new study, published in Science Translational Medicine by researchers at the University of Oxford has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models. Tonia...
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New drug a hopeful advance for incurable neurodegenerative myelin diseases
by University of Montreal Schematic representation of Pol III assembly defects caused by various mutated subunits. Representation of the 17-subunit Pol III (Pol III; reviewed in detail in 4) assembled in the presence of (A) the leukodystrophy-causative mutations encoding POLR3B-R103H, POLR1C-N32I and POLR1C-N74S and (B) the neurological disorder causative de novo mutations encoding POLR3B-A365V, POLR3B-D375V,...
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New drug shows promise for fighting both COVID-19 and cancer
by Keck School of Medicine of USC The “life cycle” of an mRNA in a eukaryotic cell. RNA is transcribed in the nucleus; processing, it is transported to the cytoplasm and translated by the ribosome. Finally, the mRNA is degraded. Credit: Public Domain While vaccination can provide life-saving protection against COVID-19, scientists are still searching...
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Resistant blood pressure: New drug proves effective in phase 2 trials
Scientists are developing new medications to treat resistant hypertension. Veejay Villafranca/Bloomberg via Getty Images Uncontrolled high blood pressure—or hypertension—affects millions of people worldwide, putting them at greater risk of serious health conditions. Research on a new drug called Baxdrostat has shown that it can substantially reduce blood pressure in people with treatment-resistant hypertension. The results...
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New drug can successfully treat patients typically resistant to high blood pressure treatment
by Queen Mary, University of London Credit: Pixabay/CC0 Public Domain A new drug called Baxdrostat has been shown to significantly reduce high blood pressure (hypertension) in patients who may not respond to current treatments for the condition, according to results from a phase II trial led jointly by a Queen Mary University of London researcher...